BACKGROUND: Pulmonary tuberculosis has been reported as a risk factor for deep venous thrombosis. AIM: In the present study we reported, physiopathological, epidemiological, clinical and therapeutic features of the association of deep venous thrombosis and pulmonary tuberculosis. METHODS: This is a retrospective study done in our department between January 2000 and December 2007. It is about 14 cases of confirmed pulmonary tuberculosis associated with deep venous thrombosis. RESULTS: It is about 14 men. The mean age was 40 years old. Pulmonary tuberculosis was confirmed by the presence of acido-alcoolo-resistant bacillus on the sputum at direct exam in 12 cases (81, 8%) and in the bronchial aspiration in 2 cases (18%). Phlebitis occurred within a mean of 20 days after the diagnosis of tuberculosis. It was confirmed by doppler deep venous ultrasound of inferior members. All patients received anti-tuberculosis drugs in association with anticoagulant treatment. Etiologic investigations showed positive anti-phospholipids antibodies in one case, and decrease in C and S proteins for 2 patients in which phlebitis was complicated by arterial pulmonary embolism. We had difficulties for controlling prothrombin level in 4 cases and we must prescribe low molecular weight heparin for 6 months in one case. CONCLUSION: A lot of attention should be done, in the follow up of pulmonary tuberculosis especially in severe presentation; because of the deep venous thrombosis's risk occurrence. Prophylactic anticoagulant treatment should be done in some cases, when the risk is higher.
BACKGROUND:Pulmonary tuberculosis has been reported as a risk factor for deep venous thrombosis. AIM: In the present study we reported, physiopathological, epidemiological, clinical and therapeutic features of the association of deep venous thrombosis and pulmonary tuberculosis. METHODS: This is a retrospective study done in our department between January 2000 and December 2007. It is about 14 cases of confirmed pulmonary tuberculosis associated with deep venous thrombosis. RESULTS: It is about 14 men. The mean age was 40 years old. Pulmonary tuberculosis was confirmed by the presence of acido-alcoolo-resistant bacillus on the sputum at direct exam in 12 cases (81, 8%) and in the bronchial aspiration in 2 cases (18%). Phlebitis occurred within a mean of 20 days after the diagnosis of tuberculosis. It was confirmed by doppler deep venous ultrasound of inferior members. All patients received anti-tuberculosis drugs in association with anticoagulant treatment. Etiologic investigations showed positive anti-phospholipids antibodies in one case, and decrease in C and S proteins for 2 patients in which phlebitis was complicated by arterial pulmonary embolism. We had difficulties for controlling prothrombin level in 4 cases and we must prescribe low molecular weight heparin for 6 months in one case. CONCLUSION: A lot of attention should be done, in the follow up of pulmonary tuberculosis especially in severe presentation; because of the deep venous thrombosis's risk occurrence. Prophylactic anticoagulant treatment should be done in some cases, when the risk is higher.
Authors: Hema Kothari; Shiva Keshava; Rit Vatsyayan; Nigel Mackman; L Vijaya Mohan Rao; Usha R Pendurthi Journal: PLoS One Date: 2014-12-02 Impact factor: 3.240
Authors: So Young Park; Sang Min Lee; Jong Wook Shin; Byoung Whui Choi; Hojoong Kim; Jae Seung Lee; Sang Do Lee; Sung Soo Park; Hwa Sik Moon; Yong Bum Park Journal: Korean J Intern Med Date: 2016-01-27 Impact factor: 2.884