BACKGROUND: Few studies have investigated work-related stress in relation to esophageal or cardia cancers. METHODS:Our nationwide Swedish population-based case-control study included 189 and 262 esophageal and cardia adenocarcinoma cases respectively, 167 esophageal squamous-cell carcinoma cases and 820 controls. We derived each study participant's occupation of longest duration from occupational histories and applied a psychosocial job-exposure matrix. Odds ratios (ORs) with 95% confidence intervals (CIs) were estimated using conditional logistic regression, in multivariable models. RESULTS: Job strain was positively associated with risk of esophageal adenocarcinoma (OR 3.2, 95% CI 1.0-9.8) and squamous-cell carcinoma (OR 4.0, 95% CI 1.6-10.5), but not with cardia adenocarcinoma. No associations regarding demands, control, social support or iso strain were observed, except for a positive association between high control and risk of esophageal squamous-cell carcinoma (OR 1.5, 95% CI 1.0-2.3). CONCLUSION: Job strain seems to increase the risk of both histological types of esophageal cancer.
RCT Entities:
BACKGROUND: Few studies have investigated work-related stress in relation to esophageal or cardia cancers. METHODS: Our nationwide Swedish population-based case-control study included 189 and 262 esophageal and cardia adenocarcinoma cases respectively, 167 esophageal squamous-cell carcinoma cases and 820 controls. We derived each study participant's occupation of longest duration from occupational histories and applied a psychosocial job-exposure matrix. Odds ratios (ORs) with 95% confidence intervals (CIs) were estimated using conditional logistic regression, in multivariable models. RESULTS: Job strain was positively associated with risk of esophageal adenocarcinoma (OR 3.2, 95% CI 1.0-9.8) and squamous-cell carcinoma (OR 4.0, 95% CI 1.6-10.5), but not with cardia adenocarcinoma. No associations regarding demands, control, social support or iso strain were observed, except for a positive association between high control and risk of esophageal squamous-cell carcinoma (OR 1.5, 95% CI 1.0-2.3). CONCLUSION: Job strain seems to increase the risk of both histological types of esophageal cancer.
Authors: Claudia Trudel-Fitzgerald; Elizabeth M Poole; Annika Idahl; Eva Lundin; Anil K Sood; Ichiro Kawachi; Laura D Kubzansky; Shelley S Tworoger Journal: Psychosom Med Date: 2017 Nov/Dec Impact factor: 4.312
Authors: Eleonor I Fransson; Solja T Nyberg; Katriina Heikkilä; Lars Alfredsson; De Dirk Bacquer; G David Batty; Sébastien Bonenfant; Annalisa Casini; Els Clays; Marcel Goldberg; France Kittel; Markku Koskenvuo; Anders Knutsson; Constanze Leineweber; Linda L Magnusson Hanson; Maria Nordin; Archana Singh-Manoux; Sakari Suominen; Jussi Vahtera; Peter Westerholm; Hugo Westerlund; Marie Zins; Töres Theorell; Mika Kivimäki Journal: BMC Public Health Date: 2012-01-20 Impact factor: 3.295
Authors: Katriina Heikkilä; Solja T Nyberg; Töres Theorell; Eleonor I Fransson; Lars Alfredsson; Jakob B Bjorner; Sébastien Bonenfant; Marianne Borritz; Kim Bouillon; Herman Burr; Nico Dragano; Goedele A Geuskens; Marcel Goldberg; Mark Hamer; Wendela E Hooftman; Irene L Houtman; Matti Joensuu; Anders Knutsson; Markku Koskenvuo; Aki Koskinen; Anne Kouvonen; Ida E H Madsen; Linda L Magnusson Hanson; Michael G Marmot; Martin L Nielsen; Maria Nordin; Tuula Oksanen; Jaana Pentti; Paula Salo; Reiner Rugulies; Andrew Steptoe; Sakari Suominen; Jussi Vahtera; Marianna Virtanen; Ari Väänänen; Peter Westerholm; Hugo Westerlund; Marie Zins; Jane E Ferrie; Archana Singh-Manoux; G David Batty; Mika Kivimäki Journal: BMJ Date: 2013-02-07
Authors: Jan Hovanec; Jack Siemiatycki; David I Conway; Ann Olsson; Pascal Guenel; Danièle Luce; Karl-Heinz Jöckel; Hermann Pohlabeln; Wolfgang Ahrens; Stefan Karrasch; Heinz-Erich Wichmann; Per Gustavsson; Dario Consonni; Franco Merletti; Lorenzo Richiardi; Simonato Lorenzo; Cristina Fortes; Marie-Élise Parent; John R McLaughlin; Paul Demers; Maria Teresa Landi; Neil Caporaso; Guillermo Fernández-Tardón; David Zaridze; Beata Świątkowska; Tamas Pándics; Jolanta Lissowska; Eleonora Fabianova; John K Field; Dana Mates; Vladimir Bencko; Lenka Foretova; Vladimir Janout; Hans Kromhout; Roel Vermeulen; Paolo Boffetta; Kurt Straif; Joachim Schüz; Swaantje Casjens; Beate Pesch; Thomas Brüning; Thomas Behrens Journal: Scand J Work Environ Health Date: 2021-05-03 Impact factor: 5.024