Literature DB >> 19925629

The optimal mode of delivery for the haemophilia carrier expecting an affected infant is vaginal delivery.

R Ljung1.   

Abstract

The optimal mode of delivery of a haemophilia carrier expecting a child is still a matter of uncertainty and debate. The aim of this commentary/review is to suggest that normal vaginal delivery should be the recommended mode of delivery for the majority of carriers, based on review of studies on obstetric aspects of haemophilia. About 2.0-4.0% of all haemophilia boys born in countries with a good standard of health care will suffer from ICH during the neonatal period. This is an average figure including all modes of delivery and regardless of whether the carrier status of the mother or the haemophilia status of the foetus was known or not at the time of delivery. On the basis of current literature, one may conclude that the risk of serious bleeding in the neonate affected with haemophilia is small in conjunction with normal vaginal delivery. It should be possible to further reduce the low frequency of complications if appropriate precautions are taken when planning the delivery in pregnant woman with known carrier status, if the sex of the foetus is known and, even more, when the haemophilia status of the foetus is known. Instrumental delivery such as use of vacuum extraction and foetal scalp monitors must be avoided at delivery of carriers.

Entities:  

Mesh:

Substances:

Year:  2009        PMID: 19925629     DOI: 10.1111/j.1365-2516.2009.02144.x

Source DB:  PubMed          Journal:  Haemophilia        ISSN: 1351-8216            Impact factor:   4.287


  5 in total

1.  Intraventricular haemorrhage and obstructive hydrocephalus in a term neonate: an uncommon presentation of haemophilia B.

Authors:  Deepanjan Bhattacharya; Indar Kumar Sharawat; Lokesh Saini
Journal:  BMJ Case Rep       Date:  2018-05-30

2.  A survey of the management of newborns with severe hemophilia in Canada.

Authors:  Paul C Moorehead; Jamie Ray; Nicholas J Barrowman; Brigitte Lemyre; Robert Klaassen
Journal:  Paediatr Child Health       Date:  2013-04       Impact factor: 2.253

3.  Complications of haemophilia in babies (first two years of life): a report from the Centers for Disease Control and Prevention Universal Data Collection System.

Authors:  R Kulkarni; R J Presley; J M Lusher; A D Shapiro; J C Gill; M Manco-Johnson; M A Koerper; T C Abshire; D DiMichele; W K Hoots; P Mathew; D J Nugent; S Geraghty; B L Evatt; J M Soucie
Journal:  Haemophilia       Date:  2016-11-04       Impact factor: 4.287

Review 4.  Update on inherited disorders of haemostasis and pregnancy.

Authors:  Orly Lavee; Giselle Kidson-Gerber
Journal:  Obstet Med       Date:  2016-01-20

5.  Mode of delivery in hemophilia: vaginal delivery and Cesarean section carry similar risks for intracranial hemorrhages and other major bleeds.

Authors:  Nadine G Andersson; Elizabeth A Chalmers; Gili Kenet; Rolf Ljung; Anne Mäkipernaa; Hervé Chambost
Journal:  Haematologica       Date:  2019-02-21       Impact factor: 9.941

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.