Literature DB >> 19924597

A paradigm for facial skin rejuvenation.

Sean D Doherty1, Christy B Doherty, Jodi S Markus, Ramsey F Markus.   

Abstract

There is a significant desire by patients to reverse the signs of aging caused by photodamage. Numerous procedures for facial skin rejuvenation have been developed in an attempt to minimize the erythema, dyspigmentation, and rhytides associated with photoaging. The initial procedures developed for facial rejuvenation involve skin resurfacing via complete ablation of layers of skin. Of these procedures, ablative laser resurfacing is the most precise technique and is considered the gold standard for facial skin rejuvenation. Although ablative procedures are quite efficacious, they carry significant patient downtime and risks of adverse effects such as scarring and dyspigmentation. Concerns regarding patient morbidity have led to the development of nonablative procedures that target dermal collagen without damaging the epidermis. Of these technologies, intense pulsed light is the most commonly used because it effectively targets both the erythema and dyspigmentation seen in photoaging. Nonablative techniques minimize side effects and patient downtime; however, they do not match the results seen in fully ablative procedures. Fractional laser technologies-first nonablative and more recently ablative-represent the most recent attempt to match the results seen in fully ablative procedures with less patient downtime. Their results are promising but require further study. Copyright Thieme Medical Publishers.

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Year:  2009        PMID: 19924597     DOI: 10.1055/s-0029-1242036

Source DB:  PubMed          Journal:  Facial Plast Surg        ISSN: 0736-6825            Impact factor:   1.446


  3 in total

Review 1.  Nonablative Fractional Laser Resurfacing in Skin of Color: Evidence-based Review.

Authors:  Shivani B Kaushik; Andrew F Alexis
Journal:  J Clin Aesthet Dermatol       Date:  2017-06-01

2.  Histological evaluation of vertical laser channels from ablative fractional resurfacing: an ex vivo pig skin model.

Authors:  Christina Skovbølling Haak; Monica Illes; Uwe Paasch; Merete Hædersdal
Journal:  Lasers Med Sci       Date:  2010-08-28       Impact factor: 3.161

3.  A randomized, placebo-controlled, single-blinded, split-faced clinical trial evaluating the efficacy and safety of KLOX-001 gel formulation with KLOX light-emitting diode light on facial rejuvenation.

Authors:  Andreas Nikolis; Steven Bernstein; Brian Kinney; Nicolo Scuderi; Shipra Rastogi; John S Sampalis
Journal:  Clin Cosmet Investig Dermatol       Date:  2016-05-13
  3 in total

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