Literature DB >> 199239

Physical evidence for an apolar binding site near the catalytic center of human alpha-thrombin.

L J Berliner, Y Y Shen.   

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Year:  1977        PMID： 199239     DOI： 10.1021/bi00640a015

Source DB:  PubMed          Journal:  Biochemistry        ISSN： 0006-2960            Impact factor:   3.162


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  9 in total

1.  Comparison of the active-site conformations of bovine alpha-thrombin and meizothrombin(desF1) by electron spin resonance.

Authors:  P D Boxrud; L J Berliner
Journal:  J Protein Chem       Date:  1996-02

2.  The structures and proteolytic specificities of autolysed human thrombin.

Authors:  J Y Chang
Journal:  Biochem J       Date:  1986-12-15       Impact factor: 3.857

3.  An acquired antithrombin autoantibody directed toward the catalytic center of the enzyme.

Authors:  P Sié; A Bezeaud; D Dupouy; G Archipoff; J M Freyssinet; J M Dugoujon; G Serre; M C Guillin; B Boneu
Journal:  J Clin Invest       Date:  1991-07       Impact factor: 14.808

4.  Structure-function relationships in human alpha- and gamma-thrombins.

Authors:  L J Berliner
Journal:  Mol Cell Biochem       Date:  1984       Impact factor: 3.396

5.  A novel allosteric pathway of thrombin inhibition: Exosite II mediated potent inhibition of thrombin by chemo-enzymatic, sulfated dehydropolymers of 4-hydroxycinnamic acids.

Authors:  Brian L Henry; Bernhard H Monien; Paul E Bock; Umesh R Desai
Journal:  J Biol Chem       Date:  2007-09-05       Impact factor: 5.157

6.  Benzyloxycarbonyl-D-Phe-Pro-methoxypropylboroglycine: a novel inhibitor of thrombin with high selectivity containing a neutral side chain at the P1 position.

Authors:  G Claeson; M Philipp; E Agner; M F Scully; R Metternich; V V Kakkar; T DeSoyza; L H Niu
Journal:  Biochem J       Date:  1993-03-01       Impact factor: 3.857

7.  The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships.

Authors:  W Bode; D Turk; A Karshikov
Journal:  Protein Sci       Date:  1992-04       Impact factor: 6.725

8.  Incorporation of the fluorescent amino acid 7-azatryptophan into the core domain 1-47 of hirudin as a probe of hirudin folding and thrombin recognition.

Authors:  Vincenzo De Filippis; Silvia De Boni; Elisa De Dea; Daniele Dalzoppo; Claudio Grandi; Angelo Fontana
Journal:  Protein Sci       Date:  2004-06       Impact factor: 6.725

9.  The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment.

Authors:  W Bode; I Mayr; U Baumann; R Huber; S R Stone; J Hofsteenge
Journal:  EMBO J       Date:  1989-11       Impact factor: 11.598
  9 in total

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