Literature DB >> 19923893

DDB2 (damaged-DNA binding protein 2) in nucleotide excision repair and DNA damage response.

Tanya Stoyanova1, Nilotpal Roy, Dragana Kopanja, Pradip Raychaudhuri, Srilata Bagchi.   

Abstract

DDB2 was identified as a protein involved in the Nucleotide Excision Repair (NER), a major DNA repair mechanism that repairs UV damage to prevent accumulation of mutations and tumorigenesis. However, recent studies indicated additional functions of DDB2 in the DNA damage response pathway. Herein, we discuss the proposed mechanisms by which DDB2 activates NER and programmed cell death upon DNA damage through its E3 ligase activity.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19923893      PMCID： PMC3107032          DOI： 10.4161/cc.8.24.10109

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


  53 in total

Review 1.  The DNA damage response: putting checkpoints in perspective.

Authors:  B B Zhou; S J Elledge
Journal:  Nature       Date:  2000-11-23       Impact factor: 49.962

2.  PUMA, a novel proapoptotic gene, is induced by p53.

Authors:  K Nakano; K H Vousden
Journal:  Mol Cell       Date:  2001-03       Impact factor: 17.970

Review 3.  COP9 signalosome revisited: a novel mediator of protein degradation.

Authors:  C Schwechheimer; X W Deng
Journal:  Trends Cell Biol       Date:  2001-10       Impact factor: 20.808

Review 4.  Cell cycle checkpoint signaling through the ATM and ATR kinases.

Authors:  R T Abraham
Journal:  Genes Dev       Date:  2001-09-01       Impact factor: 11.361

5.  Interaction between UV-damaged DNA binding activity proteins and the c-Abl tyrosine kinase.

Authors:  Feng Cong; Jean Tang; Byung Joon Hwang; Bao Q Vuong; Gilbert Chu; Stephen P Goff
Journal:  J Biol Chem       Date:  2002-07-09       Impact factor: 5.157

6.  Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress.

Authors:  K Morita; M Saitoh; K Tobiume; H Matsuura; S Enomoto; H Nishitoh; H Ichijo
Journal:  EMBO J       Date:  2001-11-01       Impact factor: 11.598

7.  Sequential binding of UV DNA damage binding factor and degradation of the p48 subunit as early events after UV irradiation.

Authors:  Vesna Rapić-Otrin; Mary P McLenigan; Dawn C Bisi; Martin Gonzalez; Arthur S Levine
Journal:  Nucleic Acids Res       Date:  2002-06-01       Impact factor: 16.971

8.  The xeroderma pigmentosum group E gene product DDB2 is a specific target of cullin 4A in mammalian cells.

Authors:  A Nag; T Bondar; S Shiv; P Raychaudhuri
Journal:  Mol Cell Biol       Date:  2001-10       Impact factor: 4.272

9.  Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome.

Authors:  S Lyapina; G Cope; A Shevchenko; G Serino; T Tsuge; C Zhou; D A Wolf; N Wei; A Shevchenko; R J Deshaies
Journal:  Science       Date:  2001-05-03       Impact factor: 47.728

10.  Hepatitis B virus X protein interacts with a probable cellular DNA repair protein.

Authors:  T H Lee; S J Elledge; J S Butel
Journal:  J Virol       Date:  1995-02       Impact factor: 5.103
View more
  25 in total

1.  Expression of DDB2 Protein in the Initiation, Progression, and Prognosis of Colorectal Cancer.

Authors:  Huaiwei Yang; Jingwei Liu; Jingjing Jing; Zeyang Wang; Yi Li; Kaihua Gou; Xue Feng; Yuan Yuan; Chengzhong Xing
Journal:  Dig Dis Sci       Date:  2018-07-27       Impact factor: 3.199

2.  DNA damage response induced by exposure of human lung adenocarcinoma cells to smoke from tobacco- and nicotine-free cigarettes.

Authors:  Ellen D Jorgensen; Hong Zhao; Frank Traganos; Anthony P Albino; Zbigniew Darzynkiewicz
Journal:  Cell Cycle       Date:  2010-06-01       Impact factor: 4.534

3.  Parp1 promotes sleep, which enhances DNA repair in neurons.

Authors:  David Zada; Yaniv Sela; Noa Matosevich; Adir Monsonego; Tali Lerer-Goldshtein; Yuval Nir; Lior Appelbaum
Journal:  Mol Cell       Date:  2021-11-18       Impact factor: 17.970

4.  DDB2 suppresses epithelial-to-mesenchymal transition in colon cancer.

Authors:  Nilotpal Roy; Prashant V Bommi; Uppoor G Bhat; Shaumick Bhattacharjee; Indira Elangovan; Jing Li; Krushna C Patra; Dragana Kopanja; Adam Blunier; Richard Benya; Srilata Bagchi; Pradip Raychaudhuri
Journal:  Cancer Res       Date:  2013-04-22       Impact factor: 12.701

5.  Tumor regression by phenethyl isothiocyanate involves DDB2.

Authors:  Nilotpal Roy; Indira Elangovan; Dragana Kopanja; Srilata Bagchi; Pradip Raychaudhuri
Journal:  Cancer Biol Ther       Date:  2012-10-31       Impact factor: 4.742

6.  NER-factor DDB2 regulates HIF1α and hypoxia-response genes in HNSCC.

Authors:  Prashant V Bommi; Vaibhav Chand; Nishit K Mukhopadhyay; Pradip Raychaudhuri; Srilata Bagchi
Journal:  Oncogene       Date:  2019-11-18       Impact factor: 9.867

Review 7.  Structural assembly of cullin-RING ubiquitin ligase complexes.

Authors:  Erik S Zimmerman; Brenda A Schulman; Ning Zheng
Journal:  Curr Opin Struct Biol       Date:  2010-09-27       Impact factor: 6.809

Review 8.  New insights into the link between DNA damage and apoptosis.

Authors:  Daniela De Zio; Valentina Cianfanelli; Francesco Cecconi
Journal:  Antioxid Redox Signal       Date:  2012-11-09       Impact factor: 8.401

9.  "Protein aggregates" contain RNA and DNA, entrapped by misfolded proteins but largely rescued by slowing translational elongation.

Authors:  Robert J Shmookler Reis; Ramani Atluri; Meenakshisundaram Balasubramaniam; Jay Johnson; Akshatha Ganne; Srinivas Ayyadevara
Journal:  Aging Cell       Date:  2021-03-31       Impact factor: 9.304

10.  Sexual dimorphism in neurological function after SCI is associated with disrupted neuroinflammation in both injured spinal cord and brain.

Authors:  Yun Li; Rodney M Ritzel; Zhuofan Lei; Tuoxin Cao; Junyun He; Alan I Faden; Junfang Wu
Journal:  Brain Behav Immun       Date:  2021-12-23       Impact factor: 7.217
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.