Literature DB >> 19923571

Identification of Western equine encephalitis virus structural proteins that confer protection after DNA vaccination.

Penelope J Gauci1, Josh Q H Wu, George A Rayner, Nicole D Barabé, Leslie P Nagata, David F Proll.   

Abstract

DNA vaccines encoding different portions of the structural proteins of western equine encephalitis virus were tested for the efficacy of their protection in a 100% lethal mouse model of the virus. The 6K-E1 structural protein encoded by the DNA vaccine conferred complete protection against challenge with the homologous strain and limited protection against challenge with a heterologous strain.

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Year:  2009        PMID： 19923571      PMCID： PMC2812089          DOI： 10.1128/CVI.00377-09

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN： 1556-679X


  12 in total

Review 1.  DNA vaccine strategies: candidates for immune modulation and immunization regimens.

Authors:  Nicole A Doria-Rose; Nancy L Haigwood
Journal:  Methods       Date:  2003-11       Impact factor: 3.608

2.  Boosting with an adenovirus-based vaccine improves protective efficacy against Venezuelan equine encephalitis virus following DNA vaccination.

Authors:  Stuart D Perkins; Lyn M O'Brien; Robert J Phillpotts
Journal:  Vaccine       Date:  2006-02-21       Impact factor: 3.641

3.  Complete genomic RNA sequence of western equine encephalitis virus and expression of the structural genes.

Authors:  D J Netolitzky; F L Schmaltz; M D Parker; G A Rayner; G R Fisher; D W Trent; D E Bader; L P Nagata
Journal:  J Gen Virol       Date:  2000-01       Impact factor: 3.891

4.  Expression, processing, and immunogenicity of the structural proteins of Venezuelan equine encephalitis virus from recombinant baculovirus vectors.

Authors:  L A Hodgson; G V Ludwig; J F Smith
Journal:  Vaccine       Date:  1999-03-05       Impact factor: 3.641

5.  Construction and characterization of monoclonal antibodies against western equine encephalitis virus.

Authors:  M C Long; L P Nagata; G V Ludwig; A Z Alvi; J D Conley; A R Bhatti; M R Suresh; R E Fulton
Journal:  Hybridoma       Date:  2000-04

6.  Intranasal immunisation with defective adenovirus serotype 5 expressing the Venezuelan equine encephalitis virus E2 glycoprotein protects against airborne challenge with virulent virus.

Authors:  R J Phillpotts; L O'brien; R E Appleton; S Carr; A Bennett
Journal:  Vaccine       Date:  2005-02-18       Impact factor: 3.641

7.  Efficacy of DNA vaccination against western equine encephalitis virus infection.

Authors:  Les P Nagata; Wei-Gang Hu; Saad A Masri; George A Rayner; Fay L Schmaltz; Dipankar Das; Josh Wu; Melissa C Long; Christine Chan; David Proll; Scott Jager; Lellean Jebailey; Mavanur R Suresh; Jonathan P Wong
Journal:  Vaccine       Date:  2005-03-18       Impact factor: 3.641

Review 8.  New insights on adenovirus as vaccine vectors.

Authors:  Marcio O Lasaro; Hildegund C J Ertl
Journal:  Mol Ther       Date:  2009-06-09       Impact factor: 11.454

9.  Virulence variation among isolates of western equine encephalitis virus in an outbred mouse model.

Authors:  Christopher H Logue; Christopher F Bosio; Thomas Welte; Kimberley M Keene; Jeremy P Ledermann; Aaron Phillips; Brian J Sheahan; Dennis J Pierro; Nicole Marlenee; Aaron C Brault; Catharine M Bosio; Amber J Singh; Ann M Powers; Ken E Olson
Journal:  J Gen Virol       Date:  2009-04-29       Impact factor: 3.891

10.  Analysis of Venezuelan equine encephalitis virus capsid protein function in the inhibition of cellular transcription.

Authors:  Natalia Garmashova; Svetlana Atasheva; Wenli Kang; Scott C Weaver; Elena Frolova; Ilya Frolov
Journal:  J Virol       Date:  2007-10-03       Impact factor: 5.103
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  4 in total

1.  Factors affecting recombinant Western equine encephalitis virus glycoprotein production in the baculovirus system.

Authors:  Ann M Toth; Christoph Geisler; Jared J Aumiller; Donald L Jarvis
Journal:  Protein Expr Purif       Date:  2011-08-16       Impact factor: 1.650

2.  Liposome-antigen-nucleic acid complexes protect mice from lethal challenge with western and eastern equine encephalitis viruses.

Authors:  Aaron T Phillips; Tony Schountz; Ann M Toth; Amber B Rico; Donald L Jarvis; Ann M Powers; Ken E Olson
Journal:  J Virol       Date:  2013-11-20       Impact factor: 5.103

Review 3.  Insights into Antibody-Mediated Alphavirus Immunity and Vaccine Development Landscape.

Authors:  Anthony Torres-Ruesta; Rhonda Sin-Ling Chee; Lisa F P Ng
Journal:  Microorganisms       Date:  2021-04-22

4.  A Multiagent Alphavirus DNA Vaccine Delivered by Intramuscular Electroporation Elicits Robust and Durable Virus-Specific Immune Responses in Mice and Rabbits and Completely Protects Mice against Lethal Venezuelan, Western, and Eastern Equine Encephalitis Virus Aerosol Challenges.

Authors:  Lesley C Dupuy; Michelle J Richards; Brian D Livingston; Drew Hannaman; Connie S Schmaljohn
Journal:  J Immunol Res       Date:  2018-06-03       Impact factor: 4.818
  4 in total

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