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Literature DB >> 1992340

Involvement of p34cdc2 in establishing the dependency of S phase on mitosis.

D Broek¹, R Bartlett, K Crawford, P Nurse.

Abstract

Mutants of cdc2+ can disrupt the dependency of S phase on completion of the previous mitosis. By changing the state of p34cdc2 it is possible to reprogramme a cell from entering mitosis to undergoing S phase. This leads to the proposal that the cell cycle can be considered a p34cdc2 cycle, and has implications for the evolution of life cycles.

Entities: Gene

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Year: 1991 PMID： 1992340 DOI： 10.1038/349388a0

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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Cited

114 in total

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Authors: T Toda; I Ochotorena; K Kominami
Journal: Philos Trans R Soc Lond B Biol Sci Date: 1999-09-29 Impact factor: 6.237

2. Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle.

Authors: E Freed; K R Lacey; P Huie; S A Lyapina; R J Deshaies; T Stearns; P K Jackson
Journal: Genes Dev Date: 1999-09-01 Impact factor: 11.361

3. Influence of the G2 cell cycle block abrogator pentoxifylline on the expression and subcellular location of cyclin B1 and p34cdc2 in HeLa cervical carcinoma cells.

Authors: T Theron; L Böhm
Journal: Cell Prolif Date: 2000-02 Impact factor: 6.831

7. Two ubiquitin-conjugating enzymes, UbcP1/Ubc4 and UbcP4/Ubc11, have distinct functions for ubiquitination of mitotic cyclin.

Authors: Hiroaki Seino; Tsutomu Kishi; Hideo Nishitani; Fumiaki Yamao
Journal: Mol Cell Biol Date: 2003-05 Impact factor: 4.272

Involvement of p34cdc2 in establishing the dependency of S phase on mitosis.

Review 1. Two distinct ubiquitin-proteolysis pathways in the fission yeast cell cycle.

2. Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle.

3. Influence of the G2 cell cycle block abrogator pentoxifylline on the expression and subcellular location of cyclin B1 and p34cdc2 in HeLa cervical carcinoma cells.

4. Plo1(+) regulates gene transcription at the M-G(1) interval during the fission yeast mitotic cell cycle.

5. Functions of fission yeast orp2 in DNA replication and checkpoint control.

6. Schizosaccharomyces pombe NIMA-related kinase, Fin1, regulates spindle formation and an affinity of Polo for the SPB.

7. Two ubiquitin-conjugating enzymes, UbcP1/Ubc4 and UbcP4/Ubc11, have distinct functions for ubiquitination of mitotic cyclin.

8. Cold-sensitive mutants of p34cdc2 that suppress a mitotic catastrophe phenotype in fission yeast.

Review 9. Eukaryotic MCM proteins: beyond replication initiation.

10. Isolation and characterization of chromosome-gain and increase-in-ploidy mutants in yeast.