Literature DB >> 19922862

Sorting out endosomes in the WASH.

James E Bear1.   

Abstract

Two new studies published in this issue of Developmental Cell by Derivery et al. and Gomez and Billadeau reveal that WASH (Wiskott-Aldrich syndrome protein and SCAR homolog) activates Arp2/3 on endosomes and plays a critical role in the fission of tubules that serve as transport intermediates during endosome sorting.

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Year:  2009        PMID: 19922862     DOI: 10.1016/j.devcel.2009.10.019

Source DB:  PubMed          Journal:  Dev Cell        ISSN: 1534-5807            Impact factor:   12.270


  6 in total

1.  Nuclear FAM21 participates in NF-κB-dependent gene regulation in pancreatic cancer cells.

Authors:  Zhi-Hui Deng; Timothy S Gomez; Douglas G Osborne; Christine A Phillips-Krawczak; Jin-San Zhang; Daniel D Billadeau
Journal:  J Cell Sci       Date:  2014-11-27       Impact factor: 5.285

2.  Stress reveals new destination for EGF receptor.

Authors:  Alejandra Tomas; Clare E Futter
Journal:  Cell Cycle       Date:  2015       Impact factor: 4.534

3.  Actin polymerization driven by WASH causes V-ATPase retrieval and vesicle neutralization before exocytosis.

Authors:  Michael Carnell; Tobias Zech; Simon D Calaminus; Seiji Ura; Monica Hagedorn; Simon A Johnston; Robin C May; Thierry Soldati; Laura M Machesky; Robert H Insall
Journal:  J Cell Biol       Date:  2011-05-23       Impact factor: 10.539

Review 4.  Regulation of the Tumor-Suppressor Function of the Class III Phosphatidylinositol 3-Kinase Complex by Ubiquitin and SUMO.

Authors:  Christina Reidick; Fouzi El Magraoui; Helmut E Meyer; Harald Stenmark; Harald W Platta
Journal:  Cancers (Basel)       Date:  2014-12-23       Impact factor: 6.639

Review 5.  Regulation of the Tumor-Suppressor BECLIN 1 by Distinct Ubiquitination Cascades.

Authors:  Fahd Boutouja; Rebecca Brinkmeier; Thomas Mastalski; Fouzi El Magraoui; Harald W Platta
Journal:  Int J Mol Sci       Date:  2017-11-27       Impact factor: 5.923

6.  The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky-Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIα.

Authors:  P V Ryder; R Vistein; A Gokhale; M N Seaman; M A Puthenveedu; V Faundez
Journal:  Mol Biol Cell       Date:  2013-05-15       Impact factor: 4.138

  6 in total

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