PURPOSE: To evaluate the clinical outcomes of LASIK using optimized "aberration neutral" ablation profiles. METHODS: Laser in situ keratomileusis was performed in 231 eyes (120 patients) with a mean spherical equivalent refraction of -4.12+/-2.26 diopters (D) (range: -0.37 to -9.50 D) using a SCHWIND Pendular microkeratome with a 130-microm cutting head and the SCHWIND ESIRIS excimer laser. In all cases, pre- and postoperative autorefractor measurements, manifest refraction, best spectacle-corrected visual acuity (BSCVA), uncorrected visual acuity (UCVA), topography and corneal wavefront analysis, and ocular wavefront analysis as well as complications were analyzed. Ablations were calculated using the ORK-CAM software. Clinical outcomes were evaluated in terms of efficacy, predictability, stability, refractive outcome, safety, and wavefront aberrations. RESULTS: At 3 months, mean spherical equivalent refraction was -0.10+/-0.33 D (range: +0.86 to -1.18 D). Of 231 eyes, 201 (87%) were within +/-0.50 D of attempted correction. Uncorrected visual acuity was 20/16 or better in 71% (164 eyes), 20/20 or better in 92% (213 eyes), and 20/32 or better in 100%. Average root-mean-square higher order aberrations increased 0.05 microm after treatment, mean spherical aberration increased 0.08 microm after treatment, and mean coma increased 0.04 microm after treatment (all for 6.0-mm analysis diameter). CONCLUSIONS: Our results show that non-customized "aberration neutral" ablation profiles derived from wavefront analysis are able to minimize the amount of induced aberrations of both the cornea and the eye. Copyright 2009, SLACK Incorporated.
PURPOSE: To evaluate the clinical outcomes of LASIK using optimized "aberration neutral" ablation profiles. METHODS: Laser in situ keratomileusis was performed in 231 eyes (120 patients) with a mean spherical equivalent refraction of -4.12+/-2.26 diopters (D) (range: -0.37 to -9.50 D) using a SCHWIND Pendular microkeratome with a 130-microm cutting head and the SCHWIND ESIRIS excimer laser. In all cases, pre- and postoperative autorefractor measurements, manifest refraction, best spectacle-corrected visual acuity (BSCVA), uncorrected visual acuity (UCVA), topography and corneal wavefront analysis, and ocular wavefront analysis as well as complications were analyzed. Ablations were calculated using the ORK-CAM software. Clinical outcomes were evaluated in terms of efficacy, predictability, stability, refractive outcome, safety, and wavefront aberrations. RESULTS: At 3 months, mean spherical equivalent refraction was -0.10+/-0.33 D (range: +0.86 to -1.18 D). Of 231 eyes, 201 (87%) were within +/-0.50 D of attempted correction. Uncorrected visual acuity was 20/16 or better in 71% (164 eyes), 20/20 or better in 92% (213 eyes), and 20/32 or better in 100%. Average root-mean-square higher order aberrations increased 0.05 microm after treatment, mean spherical aberration increased 0.08 microm after treatment, and mean coma increased 0.04 microm after treatment (all for 6.0-mm analysis diameter). CONCLUSIONS: Our results show that non-customized "aberration neutral" ablation profiles derived from wavefront analysis are able to minimize the amount of induced aberrations of both the cornea and the eye. Copyright 2009, SLACK Incorporated.