Literature DB >> 19921681

2-aryl-3-(1H-azol-1-yl)-1H-indole derivatives: a new class of antimycobacterial compounds - conventional heating in comparison with MW-assisted synthesis.

Daniele Zampieri1, Maria Grazia Mamolo, Erik Laurini, Giuditta Scialino, Elena Banfi, Luciano Vio.   

Abstract

2-Aryl-3-(1H-imidazol-1-yl and 1H-1,2,4-triazol-1-yl)-1H-indole derivatives were synthesized and tested for their in-vitro antifungal and antimycobacterial activities. These indole derivatives were devoid of antifungal activity against the tested strains of Candida spp. Yet, they exhibited an interesting antitubercular activity against Mycobacterium tuberculosis reference strain H(37)Rv.

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Year:  2009        PMID: 19921681     DOI: 10.1002/ardp.200900031

Source DB:  PubMed          Journal:  Arch Pharm (Weinheim)        ISSN: 0365-6233            Impact factor:   3.751


  1 in total

1.  Synthesis and evaluation of functionalized indoles as antimycobacterial and anticancer agents.

Authors:  Gökçe Cihan-Üstündağ; Gültaze Capan
Journal:  Mol Divers       Date:  2012-08-15       Impact factor: 2.943

  1 in total

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