OBJECTIVE: Determine and compare the prevalence of known risk factors for cardiovascular disease among unselected individuals presenting with their first ever episode of atrial flutter (AFL) and atrial fibrillation (AF). STUDY DESIGN AND SETTING: We evaluated 11 pre-selected clinical variables including age, sex, smoking history and other potential cardiac risk factors. Using the resources of the Marshfield Epidemiologic Study Area, a population-based database, all newly diagnosed cases of either AFL or AF in the region during a 4-year period were identified. RESULTS: Among the 472 incident cases, 76 (16.1%) had AFL and 396 (83.9%) had AF. Compared to those with AF, subjects with AFL were more likely to have had a history of chronic obstructive pulmonary disease (25% vs. 12%, P = 0.006), heart failure (28% vs. 17%, P = 0.05), and smoking (49% vs. 37%, P = 0.06). Hypertension, on the other hand, was more common among individuals with AF (63% vs. 47%, P = 0.01). CONCLUSION: This study represents the first report to evaluate potential differences in the conditions associated with the development of AFL versus AF. Research into the mechanisms of atrial arrhythmogenesis may lead to improved preventive and therapeutic interventions.
OBJECTIVE: Determine and compare the prevalence of known risk factors for cardiovascular disease among unselected individuals presenting with their first ever episode of atrial flutter (AFL) and atrial fibrillation (AF). STUDY DESIGN AND SETTING: We evaluated 11 pre-selected clinical variables including age, sex, smoking history and other potential cardiac risk factors. Using the resources of the Marshfield Epidemiologic Study Area, a population-based database, all newly diagnosed cases of either AFL or AF in the region during a 4-year period were identified. RESULTS: Among the 472 incident cases, 76 (16.1%) had AFL and 396 (83.9%) had AF. Compared to those with AF, subjects with AFL were more likely to have had a history of chronic obstructive pulmonary disease (25% vs. 12%, P = 0.006), heart failure (28% vs. 17%, P = 0.05), and smoking (49% vs. 37%, P = 0.06). Hypertension, on the other hand, was more common among individuals with AF (63% vs. 47%, P = 0.01). CONCLUSION: This study represents the first report to evaluate potential differences in the conditions associated with the development of AFL versus AF. Research into the mechanisms of atrial arrhythmogenesis may lead to improved preventive and therapeutic interventions.
Authors: M A Allessie; P A Boyden; A J Camm; A G Kléber; M J Lab; M J Legato; M R Rosen; P J Schwartz; P M Spooner; D R Van Wagoner ; A L Waldo Journal: Circulation Date: 2001-02-06 Impact factor: 29.690
Authors: Valentin Fuster; Lars E Rydén; David S Cannom; Harry J Crijns; Anne B Curtis; Kenneth A Ellenbogen; Jonathan L Halperin; Jean-Yves Le Heuzey; G Neal Kay; James E Lowe; S Bertil Olsson; Eric N Prystowsky; Juan Luis Tamargo; Samuel Wann; Sidney C Smith; Alice K Jacobs; Cynthia D Adams; Jeffery L Anderson; Elliott M Antman; Jonathan L Halperin; Sharon Ann Hunt; Rick Nishimura; Joseph P Ornato; Richard L Page; Barbara Riegel; Silvia G Priori; Jean-Jacques Blanc; Andrzej Budaj; A John Camm; Veronica Dean; Jaap W Deckers; Catherine Despres; Kenneth Dickstein; John Lekakis; Keith McGregor; Marco Metra; Joao Morais; Ady Osterspey; Juan Luis Tamargo; José Luis Zamorano Journal: Circulation Date: 2006-08-15 Impact factor: 29.690
Authors: Cornelis S van der Hooft; Jan Heeringa; Guy G Brusselle; Albert Hofman; Jacqueline C M Witteman; J Herre Kingma; Miriam C J M Sturkenboom; Bruno H Ch Stricker Journal: Arch Intern Med Date: 2006-05-08
Authors: Yaariv Khaykin; Nassir F Marrouche; Walid Saliba; Robert Schweikert; Dianna Bash; Michael S Chen; Michelle Williams-Andrews; Eduardo Saad; David J Burkhardt; Mandeep Bhargava; George Joseph; Antonio Rossillo; Demet Erciyes; David Martin; Andrea Natale Journal: Heart Rhythm Date: 2004-05 Impact factor: 6.343
Authors: Eleftherios M Kallergis; Emmanuel G Manios; Emmanuel M Kanoupakis; Sophia E Schiza; Hercules E Mavrakis; Nikolaos K Klapsinos; Panos E Vardas Journal: Chest Date: 2005-06 Impact factor: 9.410
Authors: Peter M Kistler; Prashanthan Sanders; Miodrag Dodic; Steven J Spence; Chrishan S Samuel; Chongxin Zhao; Jennifer A Charles; Glenn A Edwards; Jonathan M Kalman Journal: Eur Heart J Date: 2006-11-10 Impact factor: 29.983
Authors: Samuel Stempfel; Stefanie Aeschbacher; Steffen Blum; Pascal Meyre; Rebecca Gugganig; Jürg H Beer; Richard Kobza; Michael Kühne; Giorgio Moschovitis; Gianluca Menghini; Jan Novak; Stefan Osswald; Nicolas Rodondi; Elisavet Moutzouri; Matthias Schwenkglenks; Fabienne Witassek; David Conen; Christian Sticherling Journal: Int J Cardiol Heart Vasc Date: 2020-06-16
Authors: Faisal Rahman; Na Wang; Xiaoyan Yin; Patrick T Ellinor; Steven A Lubitz; Paul A LeLorier; David D McManus; Lisa M Sullivan; Sudha Seshadri; Ramachandran S Vasan; Emelia J Benjamin; Jared W Magnani Journal: Heart Rhythm Date: 2015-07-28 Impact factor: 6.343
Authors: Michael J Diamant; Jason G Andrade; Sean A Virani; Pardeep S Jhund; Mark C Petrie; Nathaniel M Hawkins Journal: ESC Heart Fail Date: 2021-09-10