Literature DB >> 19919513

An in vitro study of the antioxidant activities and effect on human DNA of the Chinese herbal decoction 'Liu Wei Di Huang'.

Yim-Tong Szeto1, Pui-Cheong Lei, Kam-Leong Ngai, Andy Tak-Wah Yiu, Catarina Sin-Pek Chan, Edith Wun-Fong Kok, Chi-Wa Leong.   

Abstract

A Chinese medicinal formulation, 'Liu Wei Di Huang', and its individual components have been tested for the genoprotective effect on human DNA by the comet assay. Results showed no DNA protection contributed by this prescription. However, the aqueous extracts of individual herbs, namely Cortex Moutan and Rhizoma Dioscoreae, were able to decrease by 10-15% the DNA stand break from hydrogen peroxide-mediated oxidative stress. This provides insight to further evaluate the interaction among herbs and the search for the active ingredient responsible for the DNA protective effect.

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Year:  2009        PMID: 19919513     DOI: 10.3109/09637480802012209

Source DB:  PubMed          Journal:  Int J Food Sci Nutr        ISSN: 0963-7486            Impact factor:   3.833


  3 in total

1.  Optimization of the extraction process for the seven bioactive compounds in Yukmijihwang-tang, an herbal formula, using response surface methodology.

Authors:  Jung-Hoon Kim; Hyeun-Kyoo Shin; Chang-Seob Seo
Journal:  Pharmacogn Mag       Date:  2014-08       Impact factor: 1.085

2.  Liuwei Dihuang (LWDH), a traditional Chinese medicinal formula, protects against β-amyloid toxicity in transgenic Caenorhabditis elegans.

Authors:  Jatinder S Sangha; Xiaoli Sun; Owen S D Wally; Kaibin Zhang; Xiuhong Ji; Zhimin Wang; Yanwen Wang; Jeffrey Zidichouski; Balakrishnan Prithiviraj; Junzeng Zhang
Journal:  PLoS One       Date:  2012-08-30       Impact factor: 3.240

3.  Yukmijihwang-Tang Suppresses Receptor Activator of Nuclear Factor Kappa-B Ligand (RANKL)-Induced Osteoclast Differentiation and Prevents Ovariectomy (OVX)-Mediated Bone Loss.

Authors:  Sang-Yong Han; Yun-Kyung Kim
Journal:  Molecules       Date:  2021-12-14       Impact factor: 4.411

  3 in total

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