| Literature DB >> 19919067 |
Huijuan Guo1, Bingda Sun, Hao Gao, Xulin Chen, Shuchun Liu, Xinsheng Yao, Xingzhong Liu, Yongsheng Che.
Abstract
New diketopiperazines, epicoccins E-H (1-4) and diphenylalazines A (5) and B (6), have been isolated from the solid-substrate fermentation culture of the Cordyceps-colonizing fungus Epicoccum nigrum. The structures of 1-6 were determined primarily by NMR experiments, and the structure of 1 was confirmed by X-ray crystallography. The absolute configurations of 3 and 5 were assigned using the modified Mosher (3) and Marfey's (5) methods, respectively. Compounds 3-5 showed inhibitory effects on HIV-1 replication in C8166 cells.Entities:
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Year: 2009 PMID： 19919067 DOI： 10.1021/np900654a
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050