Literature DB >> 19917536

Spanish Society of Medical Oncology consensus on the use of erythropoietic stimulating agents in anaemic cancer patients.

Vicente Alberola Candel1, Alfredo Carrato Mena, Eduardo Díaz-Rubio García, Pere Gascón Vilaplana, Manuel González Barón, Miguel Martín Jiménez, Emilio Alba Conejo, Javier Cassinello Espinosa, Ramon Colomer, Juan Jesús Cruz Hernández, Agustí Barnadas i Molins, Carlos Camps Herrero, Ana Ma Casas Fernández de Tejerina, Joan Carulla Torrent, Manuel Constenla Figueiras, Joaquin Gavilá Gregori, Ma Dolores Isla Casado, Bartomeu Massuti Sureda, Mariano Provencio Pulla, César Augusto Rodríguez Sánchez, Jaime Sanz Ortiz.   

Abstract

Treatment of anaemia is a very important aspect in the management of cancer patients. In order to carry out a consensus process about the use of erythropoietic stimulating agents (ESAs) in cancer patients, the Spanish Society of Medical Oncology (SEOM) elaborated a working group which coordinated a panel of medical oncology specialists. This working group has reviewed the main issues about the use of ESAs. In addition a consensus meeting was held in Madrid on 25 April 2007. The following conclusions were made: Since ESA treatment increases the haemoglobin (Hb) level and decreases the red blood cell (RBC) transfusion requirements, ESAs should be used within the approved indications in patients undergoing chemotherapy treatment, beginning at a Hb level below 11 g/dl and maintaining it around 12 g/dl, with iron supplements if necessary. Neither increasing the ESA dose in nonresponders nor the use of ESAs in the treatment of chronic cancer-related anaemia is recommended.

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Year:  2009        PMID: 19917536     DOI: 10.1007/s12094-009-0435-6

Source DB:  PubMed          Journal:  Clin Transl Oncol        ISSN: 1699-048X            Impact factor:   3.405


  82 in total

1.  Recombinant human erythropoietin in the treatment of chemotherapy-induced anemia and prevention of transfusion requirement associated with solid tumors: a randomized, controlled study.

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2.  Maintaining normal hemoglobin levels with epoetin alfa in mainly nonanemic patients with metastatic breast cancer receiving first-line chemotherapy: a survival study.

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Journal:  J Clin Oncol       Date:  2005-08-08       Impact factor: 44.544

3.  Response predicting factors to recombinant human erythropoietin in cancer patients undergoing platinum-based chemotherapy.

Authors:  Manolo González-Barón; Amdio Ordóñez; Rosa Franquesa; Manuel Constenla; Joaquin Montalar; Frederic Gili; Carlos Camps; José Felix Sancho; Pedro Pérez-Cachot
Journal:  Cancer       Date:  2002-12-01       Impact factor: 6.860

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Journal:  Eur J Cancer       Date:  2006-12-19       Impact factor: 9.162

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Journal:  J Clin Oncol       Date:  1997-03       Impact factor: 44.544

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Journal:  Blood       Date:  2000-02-15       Impact factor: 22.113

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Authors:  H Ludwig; E Fritz; H Kotzmann; P Höcker; H Gisslinger; U Barnas
Journal:  N Engl J Med       Date:  1990-06-14       Impact factor: 91.245

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Authors:  P R Ferrini; A Grossi; A M Vannucchi; G Barosi; R Guarnone; N Piva; P Musto; E Balleari
Journal:  Br J Haematol       Date:  1998-12       Impact factor: 6.998

9.  Effect of recombinant human erythropoietin on quality of life in cancer patients receiving chemotherapy: results of a randomized, controlled trial.

Authors:  Gregoris Iconomou; Angelos Koutras; Antonis Rigopoulos; Apostolos G Vagenakis; Haralabos P Kalofonos
Journal:  J Pain Symptom Manage       Date:  2003-06       Impact factor: 3.612

10.  Outcomes of cancer treatment for technology assessment and cancer treatment guidelines. American Society of Clinical Oncology.

Authors: 
Journal:  J Clin Oncol       Date:  1996-02       Impact factor: 44.544

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