Literature DB >> 19917243

p53 and Metabolism: The GAMT Connection.

Yan Zhu1, Carol Prives.   

Abstract

In this issue of Molecular Cell, Ide et al. (2009) have identified the enzyme guanidinoacetate methyltransferase (GAMT) that regulates creatine metabolism as a p53 target involved in apoptosis, reactive oxygen species (ROS), and fatty acid metabolism.

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Year:  2009        PMID: 19917243     DOI: 10.1016/j.molcel.2009.10.026

Source DB:  PubMed          Journal:  Mol Cell        ISSN: 1097-2765            Impact factor:   17.970


  10 in total

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Authors:  A Molchadsky; O Ezra; P G Amendola; D Krantz; I Kogan-Sakin; Y Buganim; N Rivlin; N Goldfinger; V Folgiero; R Falcioni; R Sarig; V Rotter
Journal:  Cell Death Differ       Date:  2013-02-15       Impact factor: 15.828

Review 2.  Autophagy-mediated tumor promotion.

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Journal:  Genes Dev       Date:  2013-07-01       Impact factor: 11.361

4.  Dysregulation of the mTOR pathway in p53-deficient mice.

Authors:  Olga V Leontieva; Liliya R Novototskaya; Geraldine M Paszkiewicz; Elena A Komarova; Andrei V Gudkov; Mikhail V Blagosklonny
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Review 5.  Tumor suppressor p53 and its mutants in cancer metabolism.

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Authors:  Liang Lei; Adam M Sonabend; Paolo Guarnieri; Craig Soderquist; Thomas Ludwig; Steven Rosenfeld; Jeffrey N Bruce; Peter Canoll
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7.  Transcriptional activator TAp63 is upregulated in muscular atrophy during ALS and induces the pro-atrophic ubiquitin ligase Trim63.

Authors:  Yannick von Grabowiecki; Paula Abreu; Orphee Blanchard; Lavinia Palamiuc; Samir Benosman; Sophie Mériaux; Véronique Devignot; Isabelle Gross; Georg Mellitzer; José L Gonzalez de Aguilar; Christian Gaiddon
Journal:  Elife       Date:  2016-02-26       Impact factor: 8.140

8.  cJun N-terminal kinase (JNK) phosphorylation of serine 36 is critical for p66Shc activation.

Authors:  Sana Khalid; Astrid Drasche; Marco Thurner; Martin Hermann; Muhammad Imtiaz Ashraf; Friedrich Fresser; Gottfried Baier; Leopold Kremser; Herbert Lindner; Jakob Troppmair
Journal:  Sci Rep       Date:  2016-02-12       Impact factor: 4.379

9.  The oxidoreductase p66Shc acts as tumor suppressor in BRAFV600E-transformed cells.

Authors:  Tobias Furlan; Sana Khalid; Anh-Vu Nguyen; Julia Günther; Jakob Troppmair
Journal:  Mol Oncol       Date:  2018-05-05       Impact factor: 6.603

10.  Tumor suppression by p53 without apoptosis and senescence: conundrum or rapalog-like gerosuppression?

Authors:  Mikhail V Blagosklonny
Journal:  Aging (Albany NY)       Date:  2012-07       Impact factor: 5.682

  10 in total

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