William W K To1, Charles K M Mok. 1. Department of Obstetrics and Gynaecology, United Christian Hospital, Hong Kong. towkw@ha.org.hk
Abstract
OBJECTIVE: To compare Doppler measurements of umbilical arteries (UAs) and veins (UV) in diabetic and nondiabetic pregnancies near term. METHODS: Consecutive patients with gestational diabetes mellitus (GDM) were prospectively recruited from a regional obstetric service over an 18-month period. Doppler assessment of the UA and UV done within 10 days from delivery were used for analysis. Similar measurements were performed in a control group of nondiabetic nonhypertensive patients near term. RESULTS: All of the Doppler waveform patterns were within normal in the cohort of 140 patients (GDM 84, normal 62). The mean PI values for the UA and the mean total umbilical venous flow (TUVF) and TUVF per unit birth weight did not differ significantly between diabetic and nondiabetic pregnancies. Large-for-gestational-age fetuses showed higher TUVF than normal size fetuses, but the TUVF per unit birth weight was higher for small-gestational-age fetuses. These differences were independent of their diabetic status. CONCLUSION: Umbilical arterial and venous Doppler measurements near term were unable to distinguish between diabetic and nondiabetic pregnancies. Umbilical venous flow volume was apparently more sensitive to the size of the fetus than to the maternal diabetic state.
OBJECTIVE: To compare Doppler measurements of umbilical arteries (UAs) and veins (UV) in diabetic and nondiabetic pregnancies near term. METHODS: Consecutive patients with gestational diabetes mellitus (GDM) were prospectively recruited from a regional obstetric service over an 18-month period. Doppler assessment of the UA and UV done within 10 days from delivery were used for analysis. Similar measurements were performed in a control group of nondiabetic nonhypertensivepatients near term. RESULTS: All of the Doppler waveform patterns were within normal in the cohort of 140 patients (GDM 84, normal 62). The mean PI values for the UA and the mean total umbilical venous flow (TUVF) and TUVF per unit birth weight did not differ significantly between diabetic and nondiabetic pregnancies. Large-for-gestational-age fetuses showed higher TUVF than normal size fetuses, but the TUVF per unit birth weight was higher for small-gestational-age fetuses. These differences were independent of their diabetic status. CONCLUSION: Umbilical arterial and venous Doppler measurements near term were unable to distinguish between diabetic and nondiabetic pregnancies. Umbilical venous flow volume was apparently more sensitive to the size of the fetus than to the maternal diabetic state.
Authors: Judith G M Jelsma; Mireille N M van Poppel; Sander Galjaard; Gernot Desoye; Rosa Corcoy; Roland Devlieger; Andre van Assche; Dirk Timmerman; Goele Jans; Jurgen Harreiter; Alexandra Kautzky-Willer; Peter Damm; Elisabeth R Mathiesen; Dorte M Jensen; Liselotte Andersen; Fidelma Dunne; Annunziata Lapolla; Graziano Di Cianni; Alessandra Bertolotto; Ewa Wender-Oegowska; Agnieszka Zawiejska; Kinga Blumska; David Hill; Pablo Rebollo; Frank J Snoek; David Simmons Journal: BMC Pregnancy Childbirth Date: 2013-07-05 Impact factor: 3.007