Literature DB >> 19914298

Effects of acute amphetamine exposure on two kinds of Pavlovian approach behavior.

John Michael Holden1, Laura L Peoples.   

Abstract

Two kinds of Pavlovian conditioned approach behavior are possible: approach of the CS (sign-tracking) and approach of the US (goal-tracking). We hypothesized that administration of AMP would increase sign-tracking and decrease goal-tracking. However, increasing doses of AMP (up to 2.0mg/kg) decreased measures of sign-tracking while simultaneously increasing measures of goal-tracking. Administration of AMP may shift responding from cues distant from the CS to cues closer to the CS. Published by Elsevier B.V.

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Year:  2009        PMID: 19914298      PMCID: PMC2822088          DOI: 10.1016/j.bbr.2009.11.014

Source DB:  PubMed          Journal:  Behav Brain Res        ISSN: 0166-4328            Impact factor:   3.332


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