Literature DB >> 19913304

Lion (Panthera leo) and cheetah (Acinonyx jubatus) IFN-gamma sequences.

Miriam Maas1, Ildiko Van Rhijn, Maria T E P Allsopp, Victor P M G Rutten.   

Abstract

Cloning and sequencing of the full length lion and cheetah interferon-gamma (IFN-gamma) transcript will enable the expression of the recombinant cytokine, to be used for production of monoclonal antibodies and to set up lion and cheetah-specific IFN-gamma ELISAs. These are relevant in blood-based diagnosis of bovine tuberculosis, an important threat to lions in the Kruger National Park. Alignment of nucleotide and amino acid sequences of lion and cheetah and that of domestic cats showed homologies of 97-100%. Copyright 2009 Elsevier B.V. All rights reserved.

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Year:  2009        PMID: 19913304     DOI: 10.1016/j.vetimm.2009.10.001

Source DB:  PubMed          Journal:  Vet Immunol Immunopathol        ISSN: 0165-2427            Impact factor:   2.046


  1 in total

1.  Adaptation and Diagnostic Potential of a Commercial Cat Interferon Gamma Release Assay for the Detection of Mycobacterium bovis Infection in African Lions (Panthera leo).

Authors:  Rachiel Gumbo; Tashnica T Sylvester; Wynand J Goosen; Peter E Buss; Lin-Mari de Klerk-Lorist; O Louis van Schalkwyk; Alicia McCall; Robin M Warren; Paul D van Helden; Michele A Miller; Tanya J Kerr
Journal:  Pathogens       Date:  2022-07-04
  1 in total

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