Literature DB >> 19913208

Safety profile of IBD: lymphoma risks.

Meenakshi Bewtra1, James D Lewis.   

Abstract

This article describes the cancer risks of commonly used inflammatory bowel disease (IBD) medications, with an emphasis on hematologic malignancy risks. The increasing use of immunosuppressant therapies in the treatment of IBD has raised this question to an even greater importance. Studies evaluating these medications are complicated due to varying disease severity and concomitant use of other immunosuppressant medication. The potential risks of all therapies must be weighed against the benefits these therapies can offer these patients.

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Year:  2009        PMID: 19913208     DOI: 10.1016/j.gtc.2009.07.004

Source DB:  PubMed          Journal:  Gastroenterol Clin North Am        ISSN: 0889-8553            Impact factor:   3.806


  7 in total

1.  Risk of lymphoma in patients with inflammatory bowel disease.

Authors:  James D Lewis
Journal:  Gastroenterol Hepatol (N Y)       Date:  2012-01

Review 2.  Top-down therapy for IBD: rationale and requisite evidence.

Authors:  Geert R D'Haens
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2010-02       Impact factor: 46.802

3.  The benefit of combination therapy depends on disease phenotype and duration in Crohn's disease.

Authors:  A N Ananthakrishnan; A Sakuraba; E L Barnes; J Pekow; L Raffals; M D Long; R S Sandler
Journal:  Aliment Pharmacol Ther       Date:  2017-05-03       Impact factor: 8.171

4.  Diabetes and the risk of infections with immunomodulator therapy in inflammatory bowel diseases.

Authors:  A N Ananthakrishnan; A Cagan; T Cai; V S Gainer; S Y Shaw; S Churchill; E W Karlson; S N Murphy; I Kohane; K P Liao
Journal:  Aliment Pharmacol Ther       Date:  2015-04-13       Impact factor: 8.171

5.  Therapy with the opioid antagonist naltrexone promotes mucosal healing in active Crohn's disease: a randomized placebo-controlled trial.

Authors:  Jill P Smith; Sandra I Bingaman; Francesca Ruggiero; David T Mauger; Aparna Mukherjee; Christopher O McGovern; Ian S Zagon
Journal:  Dig Dis Sci       Date:  2011-03-08       Impact factor: 3.199

6.  Primary effusion lymphoma-like lymphoma in a patient with inflammatory bowel disease.

Authors:  Elchanan Nussinson; Fahmi Shibli; Azmi Shahbari; Wasseem Rock; Mazen Elias; Irit Elmalah
Journal:  World J Gastroenterol       Date:  2014-01-21       Impact factor: 5.742

7.  Genetic basis of TNF-α antagonist associated psoriasis in inflammatory bowel diseases: a genotype-phenotype analysis.

Authors:  P Vedak; D Kroshinsky; J St John; R J Xavier; V Yajnik; A N Ananthakrishnan
Journal:  Aliment Pharmacol Ther       Date:  2016-01-24       Impact factor: 8.171

  7 in total

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