RATIONALE AND OBJECTIVES: Cavernous malformations (cavernomas) occur in 0.4%-0.9% of the population. The most common symptoms of cavernous malformations are seizures. An improved detection of small cavernomas might possibly help to clarify cryptogenic seizures, which represent 30% of all seizures. The aim of this study was to evaluate the benefit of magnetic resonance imaging at a field strength of 7 T in the detection of cavernomas. MATERIALS AND METHODS: Ten consecutive patients with known cavernomas were enrolled in this study. First a T2*-weighted gradient echo sequence was performed at 1.5 T with a slice thickness of 6 mm in axial orientation. Subsequently, the examination was repeated at 7 T. Both examinations were independently read by two blinded senior neuroradiologists. Localization and dimension of the hypointensities were recorded. RESULTS: One additional hypointensity was detected in one patient, which was not visible in the 1.5 T examination even retrospectively. In another patient with known cavernomatosis, innumerable new small hypointense lesions were detected at 7 T. CONCLUSION: Our small series suggests that ultra-high-field magnetic resonance imaging at 7 T improves the detection of cavernomas.
RATIONALE AND OBJECTIVES: Cavernous malformations (cavernomas) occur in 0.4%-0.9% of the population. The most common symptoms of cavernous malformations are seizures. An improved detection of small cavernomas might possibly help to clarify cryptogenic seizures, which represent 30% of all seizures. The aim of this study was to evaluate the benefit of magnetic resonance imaging at a field strength of 7 T in the detection of cavernomas. MATERIALS AND METHODS: Ten consecutive patients with known cavernomas were enrolled in this study. First a T2*-weighted gradient echo sequence was performed at 1.5 T with a slice thickness of 6 mm in axial orientation. Subsequently, the examination was repeated at 7 T. Both examinations were independently read by two blinded senior neuroradiologists. Localization and dimension of the hypointensities were recorded. RESULTS: One additional hypointensity was detected in one patient, which was not visible in the 1.5 T examination even retrospectively. In another patient with known cavernomatosis, innumerable new small hypointense lesions were detected at 7 T. CONCLUSION: Our small series suggests that ultra-high-field magnetic resonance imaging at 7 T improves the detection of cavernomas.
Authors: Janine M Lupo; Cynthia F Chuang; Susan M Chang; Igor J Barani; Bert Jimenez; Christopher P Hess; Sarah J Nelson Journal: Int J Radiat Oncol Biol Phys Date: 2011-10-12 Impact factor: 7.038
Authors: Nikolaos Mouchtouris; Nohra Chalouhi; Ameet Chitale; Robert M Starke; Stavropoula I Tjoumakaris; Robert H Rosenwasser; Pascal M Jabbour Journal: ScientificWorldJournal Date: 2015-01-05
Authors: Christoph Moenninghoff; Oliver Kraff; Stefan Maderwald; Lale Umutlu; Jens M Theysohn; Adrian Ringelstein; Karsten H Wrede; Cornelius Deuschl; Jan Altmeppen; Mark E Ladd; Michael Forsting; Harald H Quick; Marc Schlamann Journal: PLoS One Date: 2015-03-20 Impact factor: 3.240
Authors: Laurens Jl De Cocker; Arjen Lindenholz; Jaco Jm Zwanenburg; Anja G van der Kolk; Maarten Zwartbol; Peter R Luijten; Jeroen Hendrikse Journal: Neuroimage Date: 2016-11-18 Impact factor: 6.556
Authors: Giuseppe Barisano; Farshid Sepehrband; Samantha Ma; Kay Jann; Ryan Cabeen; Danny J Wang; Arthur W Toga; Meng Law Journal: Br J Radiol Date: 2018-11-01 Impact factor: 3.629