Literature DB >> 19909799

A new cytotoxic flavonoid from the fruit of Sinopodophyllum hexandrum.

Yue Kong1, Jun-Jun Xiao, Shu-Cong Meng, Xiao-Min Dong, Yue-Wei Ge, Ru-Feng Wang, Ming-Ying Shang, Shao-Qing Cai.   

Abstract

Constituents of the fruit of Sinopodophyllum hexandrum (Royle) Ying (Sinopodophylli Fructus) were investigated. A new flavonoid, 8,2'-diprenylquercetin 3-methyl ether along with 9 known compounds were isolated and identified. Among them, the new compound 8,2'-diprenylquercetin 3-methyl ether exhibited cytotoxic activities against MDA-231 and T47D breast cancer cell lines, quercetin, kaempferol and rutin were isolated from Sinopodophylli Fructus for the first time. Copyright 2009 Elsevier B.V. All rights reserved.

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Year:  2009        PMID： 19909799     DOI： 10.1016/j.fitote.2009.11.003

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  5 in total

1.  Influence of ecological factors on the production of active substances in the anti-cancer plant Sinopodophyllum hexandrum (Royle) T.S. Ying.

Authors:  Wei Liu; Jianjun Liu; Dongxue Yin; Xiaowen Zhao
Journal:  PLoS One       Date:  2015-04-15       Impact factor: 3.240

2.  Genetic diversity and structure of Sinopodophyllum hexandrum (Royle) Ying in the Qinling Mountains, China.

Authors:  Wei Liu; Dongxue Yin; Jianjun Liu; Na Li
Journal:  PLoS One       Date:  2014-10-15       Impact factor: 3.240

3.  Sixteen New Prenylated Flavonoids from the Fruit of Sinopodophyllum hexandrum.

Authors:  Yanjun Sun; Haojie Chen; Junmin Wang; Meiling Gao; Chen Zhao; Ruijie Han; Hui Chen; Meng Li; Guimin Xue; Weisheng Feng
Journal:  Molecules       Date:  2019-09-03       Impact factor: 4.411

4.  Preparative Isolation of Two Prenylated Biflavonoids from the Roots and Rhizomes of Sinopodophyllum emodi by Sephadex LH-20 Column and High-Speed Counter-Current Chromatography.

Authors:  Yan-Jun Sun; Li-Xin Pei; Kai-Bo Wang; Yin-Shi Sun; Jun-Min Wang; Yan-Li Zhang; Mei-Ling Gao; Bao-Yu Ji
Journal:  Molecules       Date:  2015-12-23       Impact factor: 4.411

Review 5.  Berberine: Botanical Occurrence, Traditional Uses, Extraction Methods, and Relevance in Cardiovascular, Metabolic, Hepatic, and Renal Disorders.

Authors:  Maria A Neag; Andrei Mocan; Javier Echeverría; Raluca M Pop; Corina I Bocsan; Gianina Crişan; Anca D Buzoianu
Journal:  Front Pharmacol       Date:  2018-08-21       Impact factor: 5.810
  5 in total

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