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Literature DB >> 19909777

Targeted hyperthermia using metal nanoparticles.

Paul Cherukuri¹, Evan S Glazer, Steven A Curley.

Abstract

Despite the use of hyperthermia to treat cancer for thousands of years, the challenge of only heating malignant cells remains daunting. In pre-clinical and early clinical trials, metal nanoparticles induce hyperthermic cytotoxicity when exposed to near-infrared radiation or radiofrequency fields. We discuss the emerging roles of nanoparticles, especially gold, in the hyperthermic treatment of cancer. In addition, we discuss the similarities of radiofrequency ablation and nanoparticle mediated cytotoxicity. Copyright 2009 Elsevier B.V. All rights reserved.

Entities: CellLine Chemical Disease Gene Species

Mesh：

Substances：
Gold

Year: 2009 PMID： 19909777 PMCID： PMC2827640 DOI： 10.1016/j.addr.2009.11.006

Source DB: PubMed Journal: Adv Drug Deliv Rev ISSN： 0169-409X Impact factor: 15.470

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