| Literature DB >> 19909285 |
Ian McGonigle1, Sarah C R Lummis.
Abstract
RDL receptors are invertebrate members of the Cys-loop family of ligand-gated ion channels. They are GABA (gamma-aminobutyric acid)-activated chloride-selective receptors that are closely related to their vertebrate orthologues, the GABA(A) receptors, as well as other Cys-loop receptors such as the ionotropic glycine, nicotinic acetylcholine and 5-HT(3) receptors. RDL receptors are widely expressed throughout the insect CNS (central nervous system) and are important in inhibitory neurotransmission. They are therefore a major insecticidal target site.Entities:
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Year: 2009 PMID: 19909285 DOI: 10.1042/BST0371404
Source DB: PubMed Journal: Biochem Soc Trans ISSN: 0300-5127 Impact factor: 5.407