Literature DB >> 19907226

Pancreatic cancer: survival, errors and evidence.

Birgir Gudjonsson1.   

Abstract

BACKGROUND: Resections for pancreatic ductal adenocarcinoma have now been carried out systematically for over 70 years. However, opinions still differ as to the results. Some consider it unresectable, whereas others claim a high survival percentage and recommend resections.
METHODS: The literature on this surgery has been scrutinized from the onset, and 790 studies have been found that deal with resections and reveal survival information.
RESULTS: Review reveals that the percentage of survivals is exaggerated with life-table methods when there is censoring of the data. Duplication of reporting survivors is rampant.
CONCLUSION: After adjusting for calculations and duplications, the total number of 5-year survivors can hardly be more than 700-800.

Entities:  

Mesh:

Year:  2009        PMID: 19907226     DOI: 10.1097/MEG.0b013e328323aab7

Source DB:  PubMed          Journal:  Eur J Gastroenterol Hepatol        ISSN: 0954-691X            Impact factor:   2.566


  10 in total

1.  Clinical validity of detecting K-ras mutations for the diagnosis of exocrine pancreatic cancer: a prospective study in a clinically-relevant spectrum of patients.

Authors:  Lucy A Parker; Miquel Porta; Blanca Lumbreras; Tomàs López; Luisa Guarner; Ildefonso Hernández-Aguado; Alfredo Carrato; Josep M Corominas; Juli Rifà; Esteve Fernandez; Joan Alguacil; Núria Malats; Francisco X Real
Journal:  Eur J Epidemiol       Date:  2011-02-06       Impact factor: 8.082

2.  The Antipancreatic Cancer Activity of OSI-027, a Potent and Selective Inhibitor of mTORC1 and mTORC2.

Authors:  Bo Chen; Ming Xu; Hui Zhang; Ming-zheng Xu; Xu-jing Wang; Qing-he Tang; Jian-ying Tang
Journal:  DNA Cell Biol       Date:  2015-08-18       Impact factor: 3.311

3.  MicroRNA profiles during galectin-9-induced apoptosis of pancreatic cancer cells.

Authors:  Ryoichi Okura; Shintaro Fujihara; Hisakazu Iwama; Asahiro Morishita; Taiga Chiyo; Miwako Watanabe; Kayo Hirose; Kiyoyuki Kobayashi; Takayuki Fujimori; Kiyohito Kato; Hideki Kamada; Hideki Kobara; Hirohito Mori; Toshiro Niki; Mitsuomi Hirashima; Keiichi Okano; Yasuyuki Suzuki; Tsutomu Masaki
Journal:  Oncol Lett       Date:  2017-11-01       Impact factor: 2.967

4.  Polyphenol-rich extract of Salvia chinensis exhibits anticancer activity in different cancer cell lines, and induces cell cycle arrest at the G₀/G₁-phase, apoptosis and loss of mitochondrial membrane potential in pancreatic cancer cells.

Authors:  Quan Zhao; Xue-Chen Huo; Fu-Dong Sun; Rui-Qian Dong
Journal:  Mol Med Rep       Date:  2015-07-13       Impact factor: 2.952

Review 5.  Pancreatic Cancer: 80 Years of Surgery-Percentage and Repetitions.

Authors:  Birgir Gudjonsson
Journal:  HPB Surg       Date:  2016-10-25

6.  Expression of Glut-1 and HK-II in Pancreatic Cancer and Their Impact on Prognosis and FDG Accumulation.

Authors:  Hai-Jing Yang; Wei-Jia Xu; Yi-Hui Guan; Hui-Wei Zhang; Wei-Qun Ding; Lan Rong; Zhi-Bing Qiu; Liang Zhong
Journal:  Transl Oncol       Date:  2016-12       Impact factor: 4.243

7.  Cutting off the fuel supply to calcium pumps in pancreatic cancer cells: role of pyruvate kinase-M2 (PKM2).

Authors:  Andrew D James; Daniel A Richardson; In-Whan Oh; Pishyaporn Sritangos; Thomas Attard; Lisa Barrett; Jason I E Bruce
Journal:  Br J Cancer       Date:  2019-12-10       Impact factor: 7.640

8.  Antiproliferative effect of alpinetin in BxPC-3 pancreatic cancer cells.

Authors:  Jian Du; Bo Tang; Jingwen Wang; Hongtao Sui; Xueli Jin; Liming Wang; Zhongyu Wang
Journal:  Int J Mol Med       Date:  2012-01-11       Impact factor: 4.101

9.  Long-Term Diabetes Mellitus Is Associated with an Increased Risk of Pancreatic Cancer: A Meta-Analysis.

Authors:  Shanshan Song; Baosheng Wang; Xin Zhang; Liliang Hao; Xianliang Hu; Zhongxiang Li; Shaolong Sun
Journal:  PLoS One       Date:  2015-07-29       Impact factor: 3.240

10.  Glycolytic ATP fuels the plasma membrane calcium pump critical for pancreatic cancer cell survival.

Authors:  Andrew D James; Anthony Chan; Oihane Erice; Ajith K Siriwardena; Jason I E Bruce
Journal:  J Biol Chem       Date:  2013-10-24       Impact factor: 5.157

  10 in total

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