Literature DB >> 19903872

Challenges to optimal enteral nutrition in a multidisciplinary pediatric intensive care unit.

Nilesh M Mehta1, Dianne McAleer, Susan Hamilton, Elizabeth Naples, Kristen Leavitt, Paul Mitchell, Christopher Duggan.   

Abstract

OBJECTIVE: To describe nutrient intake in critically ill children, identify risk factors associated with avoidable interruptions to enteral nutrition (EN), and highlight opportunities to improve enteral nutrient delivery in a busy tertiary pediatric intensive care unit (PICU). Design, Setting, and Measurements: Daily nutrient intake and factors responsible for avoidable interruptions to EN were recorded in patients admitted to a 29-bed medical and surgical PICU over 4 weeks. Clinical characteristics, time to reach caloric goal, and parenteral nutrition (PN) use were compared between patients with and without avoidable interruptions to EN.
RESULTS: Daily record of nutrient intake was obtained in 117 consecutive patients (median age, 7 years). Eighty (68%) patients received EN (20% postpyloric) for a total of 381 EN days (median, 2 days). Median time to EN initiation was less than 1 day. However, EN was subsequently interrupted in 24 (30%) patients at an average of 3.7 +/- 3.1 times per patient (range, 1-13), for a total of 88 episodes accounting for 1,483 hours of EN deprivation in this cohort. Of the 88 episodes of EN interruption, 51 (58%) were deemed as avoidable. Mechanically ventilated subjects were at the highest risk of EN interruptions. Avoidable EN interruption was associated with increased reliance on PN and impaired ability to reach caloric goal.
CONCLUSIONS: EN interruption is common and frequently avoidable in critically ill children. Knowledge of existing barriers to EN such as those identified in this study will allow appropriate interventions to optimize nutrition provision in the PICU.

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Year:  2009        PMID: 19903872      PMCID: PMC4902117          DOI: 10.1177/0148607109348065

Source DB:  PubMed          Journal:  JPEN J Parenter Enteral Nutr        ISSN: 0148-6071            Impact factor:   4.016


  28 in total

1.  Enteral nutrition in the early postoperative period: a new semi-elemental formula versus total parenteral nutrition.

Authors:  E Hamaoui; R Lefkowitz; L Olender; E Krasnopolsky-Levine; M Favale; H Webb; E L Hoover
Journal:  JPEN J Parenter Enteral Nutr       Date:  1990 Sep-Oct       Impact factor: 4.016

2.  Oral and nasal enteral tube placement errors and complications in a pediatric intensive care unit.

Authors:  Amy M Creel; Margaret K Winkler
Journal:  Pediatr Crit Care Med       Date:  2007-03       Impact factor: 3.624

Review 3.  Clinical benefits of early post-injury enteral feeding.

Authors:  F A Moore; E E Moore; J B Haenel
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4.  Continuation of transpyloric feeding during weaning of mechanical ventilation and tracheal extubation in children: a randomized controlled trial.

Authors:  Kim A Lyons; Richard J Brilli; Renee A Wieman; Brian R Jacobs
Journal:  JPEN J Parenter Enteral Nutr       Date:  2002 May-Jun       Impact factor: 4.016

5.  Enteral tube feeding in the intensive care unit: factors impeding adequate delivery.

Authors:  S A McClave; L K Sexton; D A Spain; J L Adams; N A Owens; M B Sullins; B S Blandford; H L Snider
Journal:  Crit Care Med       Date:  1999-07       Impact factor: 7.598

Review 6.  Parenteral vs. enteral nutrition in the critically ill patient: a meta-analysis of trials using the intention to treat principle.

Authors:  Fiona Simpson; Gordon Stuart Doig
Journal:  Intensive Care Med       Date:  2004-12-09       Impact factor: 17.440

7.  A study of problems associated with the delivery of enteral feed in critically ill patients in five ICUs in the UK.

Authors:  S Adam; S Batson
Journal:  Intensive Care Med       Date:  1997-03       Impact factor: 17.440

8.  Malnutrition, nutritional indices, and early enteral feeding in critically ill children.

Authors:  G Briassoulis; N Zavras; T Hatzis
Journal:  Nutrition       Date:  2001 Jul-Aug       Impact factor: 4.008

9.  Gastric emptying in mechanically ventilated critically ill patients: effect of neuromuscular blocking agent.

Authors:  Fabienne Tamion; Karine Hamelin; Annie Duflo; Christophe Girault; Jean-Christophe Richard; Guy Bonmarchand
Journal:  Intensive Care Med       Date:  2003-07-30       Impact factor: 17.440

10.  Severe weight loss and hypermetabolic paroxysmal dysautonomia following hypoxic ischemic brain injury: the role of indirect calorimetry in the intensive care unit.

Authors:  Nilesh M Mehta; Lori J Bechard; Kristen Leavitt; Christopher Duggan
Journal:  JPEN J Parenter Enteral Nutr       Date:  2008 May-Jun       Impact factor: 4.016

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  31 in total

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Authors:  Enid E Martinez; Katherine Douglas; Samuel Nurko; Nilesh M Mehta
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2.  Adequate enteral protein intake is inversely associated with 60-d mortality in critically ill children: a multicenter, prospective, cohort study.

Authors:  Nilesh M Mehta; Lori J Bechard; David Zurakowski; Christopher P Duggan; Daren K Heyland
Journal:  Am J Clin Nutr       Date:  2015-05-13       Impact factor: 7.045

Review 3.  A review of feeding intolerance in critically ill children.

Authors:  Lyvonne N Tume; Frédéric V Valla
Journal:  Eur J Pediatr       Date:  2018-08-17       Impact factor: 3.183

4.  Non-Thyroidal Illness Syndrome in Critically Ill Children: Prognostic Value and Impact of Nutritional Management.

Authors:  An Jacobs; Inge Derese; Sarah Vander Perre; Esther van Puffelen; Sören Verstraete; Lies Pauwels; Sascha Verbruggen; Pieter Wouters; Lies Langouche; Gonzalo Garcia Guerra; Koen Joosten; Ilse Vanhorebeek; Greet Van den Berghe
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Review 5.  An integrated systematic review and meta-analysis of published randomized controlled trials evaluating nasogastric against postpyloris (nasoduodenal and nasojejunal) feeding in critically ill patients admitted in intensive care unit.

Authors:  M S Sajid; A Harper; Q Hussain; L Forni; K K Singh
Journal:  Eur J Clin Nutr       Date:  2014-02-12       Impact factor: 4.016

6.  Time of parenteral nutrition in paediatric critical care patients, prior nutritional status probably makes the difference?

Authors:  Mònica Balaguer; Iolanda Jordan
Journal:  J Thorac Dis       Date:  2016-08       Impact factor: 2.895

7.  Early Enteral Nutrition Is Associated With Improved Clinical Outcomes in Critically Ill Children: A Secondary Analysis of Nutrition Support in the Heart and Lung Failure-Pediatric Insulin Titration Trial.

Authors:  Vijay Srinivasan; Natalie R Hasbani; Nilesh M Mehta; Sharon Y Irving; Sarah B Kandil; H Christine Allen; Katri V Typpo; Natalie Z Cvijanovich; E Vincent S Faustino; David Wypij; Michael S D Agus; Vinay M Nadkarni
Journal:  Pediatr Crit Care Med       Date:  2020-03       Impact factor: 3.624

Review 8.  Pediatric Multiple Organ Dysfunction Syndrome: Promising Therapies.

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Journal:  Pediatr Crit Care Med       Date:  2017-03       Impact factor: 3.624

9.  Nutrition support among critically ill children with AKI.

Authors:  Ursula G Kyle; Ayse Akcan-Arikan; Renán A Orellana; Jorge A Coss-Bu
Journal:  Clin J Am Soc Nephrol       Date:  2013-01-04       Impact factor: 8.237

10.  Enteral Nutrition and Acid-Suppressive Therapy in the PICU: Impact on the Risk of Ventilator-Associated Pneumonia.

Authors:  Ben D Albert; David Zurakowski; Lori J Bechard; Gregory P Priebe; Christopher P Duggan; Daren K Heyland; Nilesh M Mehta
Journal:  Pediatr Crit Care Med       Date:  2016-10       Impact factor: 3.624

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