Literature DB >> 19903072

Molecular and cellular biology of rhabdomyosarcoma.

Carla De Giovanni1, Lorena Landuzzi, Giordano Nicoletti, Pier-Luigi Lollini, Patrizia Nanni.   

Abstract

Rhabdomyosarcoma is a group of soft-tissue sarcomas that share features of skeletal myogenesis, but show extensive heterogeneity in histology, age and site of onset, and prognosis. This review matches recent molecular data with biological features of rhabdomyosarcoma. Alterations in molecular pathways, animal models, cell of origin and potential new therapeutic targets are discussed.

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Mesh：

Year:  2009        PMID： 19903072     DOI： 10.2217/fon.09.97

Source DB:  PubMed          Journal:  Future Oncol        ISSN： 1479-6694            Impact factor:   3.404


  44 in total

1.  Perianal rhabdomyosarcoma presenting 21 months after hamartoma excision.

Authors:  N Piché; N Patey; D Dal Soglio; Y Samson; S Bouchard
Journal:  Pediatr Surg Int       Date:  2012-03-20       Impact factor: 1.827

Review 2.  Enhancer of zeste homolog 2 (EZH2) in pediatric soft tissue sarcomas: first implications.

Authors:  Roberta Ciarapica; Lucio Miele; Antonio Giordano; Franco Locatelli; Rossella Rota
Journal:  BMC Med       Date:  2011-05-25       Impact factor: 8.775

3.  CDK4 Amplification Reduces Sensitivity to CDK4/6 Inhibition in Fusion-Positive Rhabdomyosarcoma.

Authors:  Mary E Olanich; Wenyue Sun; Stephen M Hewitt; Zied Abdullaev; Svetlana D Pack; Frederic G Barr
Journal:  Clin Cancer Res       Date:  2015-03-25       Impact factor: 12.531

4.  Tumor suppressor genes promote rhabdomyosarcoma progression in p53 heterozygous, HER-2/neu transgenic mice.

Authors:  Marianna L Ianzano; Stefania Croci; Giordano Nicoletti; Arianna Palladini; Lorena Landuzzi; Valentina Grosso; Dario Ranieri; Massimiliano Dall'Ora; Ilaria Santeramo; Milena Urbini; Carla De Giovanni; Pier-Luigi Lollini; Patrizia Nanni
Journal:  Oncotarget       Date:  2014-01-15

Review 5.  Childhood rhabdomyosarcoma: recent advances and prospective views.

Authors:  C Wang
Journal:  J Dent Res       Date:  2011-09-13       Impact factor: 6.116

Review 6.  Childhood rhabdomyosarcoma: new insight on biology and treatment.

Authors:  Winston W Huh; Stephen X Skapek
Journal:  Curr Oncol Rep       Date:  2010-11       Impact factor: 5.075

7.  Furin targeted drug delivery for treatment of rhabdomyosarcoma in a mouse model.

Authors:  Katarina Hajdin; Valentina D'Alessandro; Felix K Niggli; Beat W Schäfer; Michele Bernasconi
Journal:  PLoS One       Date:  2010-05-03       Impact factor: 3.240

Review 8.  MicroRNAs in skeletal muscle biology and exercise adaptation.

Authors:  Tyler J Kirby; John J McCarthy
Journal:  Free Radic Biol Med       Date:  2013-07-18       Impact factor: 7.376

9.  Small molecule inhibition of PAX3-FOXO1 through AKT activation suppresses malignant phenotypes of alveolar rhabdomyosarcoma.

Authors:  Mathivanan Jothi; Munmun Mal; Charles Keller; Asoke K Mal
Journal:  Mol Cancer Ther       Date:  2013-10-09       Impact factor: 6.261

10.  Overexpression of the skNAC gene in human rhabdomyosarcoma cells enhances their differentiation potential and inhibits tumor cell growth and spreading.

Authors:  Janine Berkholz; Weronika Kuzyniak; Michael Hoepfner; Barbara Munz
Journal:  Clin Exp Metastasis       Date:  2014-09-11       Impact factor: 5.150
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