Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Assessing the value of autologous and allogeneic cells for regenerative medicine.

Literature DB >> 19903003

Assessing the value of autologous and allogeneic cells for regenerative medicine.

Abstract

The advantages and disadvantages of autologous and allogeneic human cells for regenerative medicine are summarized. The comparison of relative advantages includes: ease and cost of treating large numbers of patients, the speed of availability of therapy and the differing complexity of the development pathways. The comparison of relative disadvantages deals with issues such as variability of source material, the risks of cell abnormality and of viral and prion contamination, and the sensitive issues surrounding use of embryo-derived cells. From the comparisons, several potentially decisive issues are drawn out, such as possible immune response and teratoma formation, the impact of patents and the virtues of hospital versus industry-centered development.

Entities: Disease Species

Mesh：

Year: 2009 PMID： 19903003 DOI： 10.2217/rme.09.64

Source DB: PubMed Journal: Regen Med ISSN： 1746-0751 Impact factor: 3.806

Keyword Cloud
Cited

18 in total

1. Customized Ca-P/PHBV nanocomposite scaffolds for bone tissue engineering: design, fabrication, surface modification and sustained release of growth factor.

Authors: Bin Duan; Min Wang
Journal: J R Soc Interface Date: 2010-05-26 Impact factor: 4.118

2. Delayed minimally invasive injection of allogenic bone marrow stromal cell sheets regenerates large bone defects in an ovine preclinical animal model.

Authors: Arne Berner; Jan Henkel; Maria A Woodruff; Roland Steck; Michael Nerlich; Michael A Schuetz; Dietmar W Hutmacher
Journal: Stem Cells Transl Med Date: 2015-04-01 Impact factor: 6.940

3. Enhanced survival and neurite network formation of human umbilical cord blood neuronal progenitors in three-dimensional collagen constructs.

Authors: Marian M Bercu; Hadar Arien-Zakay; Dana Stoler; Shimon Lecht; Peter I Lelkes; Simcha Samuel; Reuven Or; Arnon Nagler; Philip Lazarovici; Uriel Elchalal
Journal: J Mol Neurosci Date: 2012-12-12 Impact factor: 3.444

Review 4. Concise review: cell therapies: the route to widespread adoption.

Authors: Lucy Foley; Michael Whitaker
Journal: Stem Cells Transl Med Date: 2012-05-09 Impact factor: 6.940

Review 5. Immunology and cartilage regeneration.

Authors: Benjamin Smith; Ian R Sigal; Daniel A Grande
Journal: Immunol Res Date: 2015-12 Impact factor: 2.829

6. Sourcing of an alternative pericyte-like cell type from peripheral blood in clinically relevant numbers for therapeutic angiogenic applications.

Authors: Anna Blocki; Yingting Wang; Maria Koch; Anna Goralczyk; Sebastian Beyer; Nikita Agarwal; Michelle Lee; Shehzahdi Moonshi; Jean-Yves Dewavrin; Priscilla Peh; Herbert Schwarz; Kishore Bhakoo; Michael Raghunath
Journal: Mol Ther Date: 2014-12-12 Impact factor: 11.454

Assessing the value of autologous and allogeneic cells for regenerative medicine.

1. Customized Ca-P/PHBV nanocomposite scaffolds for bone tissue engineering: design, fabrication, surface modification and sustained release of growth factor.

2. Delayed minimally invasive injection of allogenic bone marrow stromal cell sheets regenerates large bone defects in an ovine preclinical animal model.

3. Enhanced survival and neurite network formation of human umbilical cord blood neuronal progenitors in three-dimensional collagen constructs.

Review 4. Concise review: cell therapies: the route to widespread adoption.

Review 5. Immunology and cartilage regeneration.

6. Sourcing of an alternative pericyte-like cell type from peripheral blood in clinically relevant numbers for therapeutic angiogenic applications.

7. The Survey on Cellular and Tissue-Engineered Therapies in Europe in 2016 and 2017.

Review 8. Bone Regeneration Based on Tissue Engineering Conceptions - A 21st Century Perspective.

9. Innovative regenerative medicines in the EU: a better future in evidence?

10. Nonhuman primate induced pluripotent stem cells in regenerative medicine.