Literature DB >> 19902939

A stereoselective approach to nucleosides and 4'-thioanalogues from acyclic precursors.

Daniel Chapdelaine1, Benoit Cardinal-David, Michel Prévost, Marc Gagnon, Isabelle Thumin, Yvan Guindon.   

Abstract

D- and L-nucleosides and analogues thereof, including the 4'-thionucleoside series, are one of the most important biological and pharmaceutically active classes of compounds. A novel approach to their synthesis from chiral acyclic thioaminal, bearing the nucleobase, is described.

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Year:  2009        PMID: 19902939     DOI: 10.1021/ja905452f

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  1 in total

1.  Using Neighboring-Group Participation for Acyclic Stereocontrol in Diastereoselective Substitution Reactions of Acetals.

Authors:  Amanda Ramdular; K A Woerpel
Journal:  Org Lett       Date:  2020-05-11       Impact factor: 6.005

  1 in total

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