Literature DB >> 19902596

[Risk factors for suicide attempts in dual diagnosis patients].

Yuri Gimelfarb1, Zipi Natan.   

Abstract

BACKGROUND: Patients suffering from both psychiatric disorders and substance abuse/addiction are titled "dual diagnosis patients" (DDP). Substance abuse/addiction is associated with suicidal behavior. Although our knowledge of substance abuse/addiction and suicide behavior is increasing, we lack sufficient knowledge of suicide among DDP.
OBJECTIVES: (1) To compare the rate of suicide attempts among DDP and non-DDP; (2) To determine risk factors for suicide attempts in DDP.
METHODS: Analysis of 3,433 consecutive admissions: men and women aged 18-65 years in our center (06/2003-06/2005).
RESULTS: Of 848 DDPs' admissions, 197 (23.2%) were after suicide attempts, whereas 403 of 2558 non-DDP's admissions (15.8%) were after suicide attempts (odds ratio [OR] = 1.6; 95% confidence interval [95% CI] = 1.3 - 1.9). The OR in the multiple analysis was 1.4 [95% CI] = 1.1 - 1.8). By multivariate regression analysis, the positive result for Tetrahydrocannabinol (THC) in the urine analysis was a protective factor and a diagnosis of disorders of adult personality and behavior (according to the International Classification of Disease - 10 edition [ICD-10]) was an independent risk factor for suicide attempts.
CONCLUSIONS: DDP have greater risks of suicide attempts than non-DDP. A comprehensive plan of preventive interventions for multidisciplinary staff is recommended in order to reduce suicide rates in DDP.

Entities:  

Mesh:

Year:  2009        PMID: 19902596

Source DB:  PubMed          Journal:  Harefuah        ISSN: 0017-7768


  2 in total

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Authors:  José Jaime Martínez-Magaña; Alma Delia Genis-Mendoza; Jorge Ameth Villatoro Velázquez; Marycarmen Bustos-Gamiño; Isela Esther Juárez-Rojop; Carlos Alfonso Tovilla-Zarate; Emmanuel Sarmiento; Erasmo Saucedo; Oscar Rodríguez-Mayoral; Clara Fleiz-Bautista; Beatriz Camarena; Alejandro Aguilar; Thelma Beatriz Gonzalez-Castro; María Elena Medina-Mora; Humberto Nicolini
Journal:  Sci Rep       Date:  2021-03-24       Impact factor: 4.379

2.  Association of FAAH p.Pro129Thr and COMT p.Ala72Ser with schizophrenia and comorbid substance use through next-generation sequencing: an exploratory analysis.

Authors:  José J Martínez-Magaña; Alma D Genis-Mendoza; Vanessa González-Covarrubias; Isela E Juárez-Rojop; Carlos A Tovilla-Zárate; Xavier Soberón; Nuria Lanzagorta; Humberto Nicolini
Journal:  Braz J Psychiatry       Date:  2022 Mar-Abr
  2 in total

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