Literature DB >> 19902110

Spontaneous aneuploidy and clone formation in adipose tissue stem cells during different periods of culturing.

O A Buyanovskaya1, N P Kuleshov, V A Nikitina, E S Voronina, L D Katosova, N P Bochkov.   

Abstract

Cytogenetic analysis of 13 mesenchymal stem cell cultures isolated from normal human adipose tissue was carried out at different stages of culturing. The incidence of chromosomes 6, 8, 11, and X aneuploidy and polyploidy was studied by fluorescent in situ hybridization. During the early passages, monosomal cells were more often detected than trisomal ones. A clone with chromosome 6 monosomy was detected in three cultures during late passages.

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Year:  2009        PMID: 19902110     DOI: 10.1007/s10517-009-0647-3

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN: 0007-4888            Impact factor:   0.804


  15 in total

Review 1.  Mesenchymal stem cells as therapeutics and vehicles for gene and drug delivery.

Authors:  Christopher D Porada; Graça Almeida-Porada
Journal:  Adv Drug Deliv Rev       Date:  2010-09-07       Impact factor: 15.470

Review 2.  Circulating exosomes in obstructive sleep apnea as phenotypic biomarkers and mechanistic messengers of end-organ morbidity.

Authors:  Abdelnaby Khalyfa; Leila Kheirandish-Gozal; David Gozal
Journal:  Respir Physiol Neurobiol       Date:  2017-07-01       Impact factor: 1.931

3.  Effects of donors' age and passage number on the biological characteristics of menstrual blood-derived stem cells.

Authors:  Jinyang Chen; Xiaochun Du; Qian Chen; Charlie Xiang
Journal:  Int J Clin Exp Pathol       Date:  2015-11-01

4.  Safety of mesenchymal stem cells for clinical application.

Authors:  Youwei Wang; Zhi-Bo Han; Yong-Ping Song; Zhong Chao Han
Journal:  Stem Cells Int       Date:  2012-05-16       Impact factor: 5.443

5.  Human adipose stromal cells (ASC) for the regeneration of injured cartilage display genetic stability after in vitro culture expansion.

Authors:  Simona Neri; Philippe Bourin; Julie-Anne Peyrafitte; Luca Cattini; Andrea Facchini; Erminia Mariani
Journal:  PLoS One       Date:  2013-10-28       Impact factor: 3.240

6.  The application of an in situ karyotyping technique for mesenchymal stromal cells: a validation and comparison study with classical G-banding.

Authors:  Sang Mee Hwang; Cha-Ja See; Jungeun Choi; Seon Young Kim; Qute Choi; Jung Ah Kim; Jiseok Kwon; Si Nae Park; Kyongok Im; Il-Hoan Oh; Dong Soon Lee
Journal:  Exp Mol Med       Date:  2013-12-20       Impact factor: 8.718

7.  Long-term cultured mesenchymal stem cells frequently develop genomic mutations but do not undergo malignant transformation.

Authors:  Y Wang; Z Zhang; Y Chi; Q Zhang; F Xu; Z Yang; L Meng; S Yang; S Yan; A Mao; J Zhang; Y Yang; S Wang; J Cui; L Liang; Y Ji; Z-B Han; X Fang; Z C Han
Journal:  Cell Death Dis       Date:  2013-12-05       Impact factor: 8.469

8.  Genetic evaluation of mesenchymal stem cells.

Authors:  Déborah Afonso Cornélio; Silvia Regina Batistuzzo de Medeiros
Journal:  Rev Bras Hematol Hemoter       Date:  2014-06-02

Review 9.  Mesenchymal stem cell-derived microparticles: a promising therapeutic strategy.

Authors:  Xi Tan; Yong-Zhen Gong; Ping Wu; Duan-Fang Liao; Xi-Long Zheng
Journal:  Int J Mol Sci       Date:  2014-08-18       Impact factor: 5.923

10.  In Vivo therapeutic potential of mesenchymal stem cell-derived extracellular vesicles with optical imaging reporter in tumor mice model.

Authors:  Senthilkumar Kalimuthu; Prakash Gangadaran; Xiu Juan Li; Ji Min Oh; Ho Won Lee; Shin Young Jeong; Sang-Woo Lee; Jaetae Lee; Byeong-Cheol Ahn
Journal:  Sci Rep       Date:  2016-07-25       Impact factor: 4.379

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