| Literature DB >> 19902093 |
S B Seredenin1, T A Antipova, M V Voronin, S Yu Kurchashova, A N Kuimov.
Abstract
In vitro radioligand assay revealed interaction of afobazole with sigma(1)-receptors (Ki=5.9x10(-6) M). Translocation of sigma(1)-receptors from the endoplasmic reticulum to the outer membrane was demonstrated by confocal microscopy. Experiments were performed on the model of HT-22 immortalized hippocampal cells after incubation with afobazole in a concentration of 10(-8) M.Entities:
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Year: 2009 PMID： 19902093 DOI： 10.1007/s10517-009-0624-x
Source DB: PubMed Journal: Bull Exp Biol Med ISSN： 0007-4888 Impact factor: 0.804