Literature DB >> 19901525

Drugging the heat shock factor 1 pathway: exploitation of the critical cancer cell dependence on the guardian of the proteome.

Emmanuel de Billy, Marissa V Powers, Jennifer R Smith, Paul Workman.   

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Year:  2009        PMID： 19901525     DOI： 10.4161/cc.8.23.10423

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  19 in total

Review 1.  Protein folding in the cytoplasm and the heat shock response.

Authors:  R Martin Vabulas; Swasti Raychaudhuri; Manajit Hayer-Hartl; F Ulrich Hartl
Journal:  Cold Spring Harb Perspect Biol       Date:  2010-12       Impact factor: 10.005

2.  High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer.

Authors:  Sandro Santagata; Rong Hu; Nancy U Lin; Marc L Mendillo; Laura C Collins; Susan E Hankinson; Stuart J Schnitt; Luke Whitesell; Rulla M Tamimi; Susan Lindquist; Tan A Ince
Journal:  Proc Natl Acad Sci U S A       Date:  2011-10-31       Impact factor: 11.205

3.  FTO promotes multiple myeloma progression by posttranscriptional activation of HSF1 in an m6A-YTHDF2-dependent manner.

Authors:  Aoshuang Xu; Jiasi Zhang; Liping Zuo; Han Yan; Lei Chen; Fei Zhao; Fengjuan Fan; Jian Xu; Bo Zhang; Yuyang Zhang; Xuejiao Yin; Qianwen Cheng; Su Gao; Jun Deng; Heng Mei; Zhiping Huang; Chunyan Sun; Yu Hu
Journal:  Mol Ther       Date:  2021-12-13       Impact factor: 11.454

4.  Nucleoside analog inhibits microRNA-214 through targeting heat-shock factor 1 in human epithelial ovarian cancer.

Authors:  Yi-Fei Chen; Zhangli Dong; Yi Xia; Jingjie Tang; Ling Peng; Shuying Wang; Dongmei Lai
Journal:  Cancer Sci       Date:  2013-10-22       Impact factor: 6.716

5.  Identification of mixed lineage leukemia 1(MLL1) protein as a coactivator of heat shock factor 1(HSF1) protein in response to heat shock protein 90 (HSP90) inhibition.

Authors:  Yaoyu Chen; Jinyun Chen; Jianjun Yu; Guizhi Yang; Emilia Temple; Fred Harbinski; Hui Gao; Christopher Wilson; Raymond Pagliarini; Wenlai Zhou
Journal:  J Biol Chem       Date:  2014-05-15       Impact factor: 5.157

6.  A stressful life (or death): combinatorial proteotoxic approaches to cancer-selective therapeutic vulnerability.

Authors:  Paul Workman; Faith E Davies
Journal:  Oncotarget       Date:  2011-04

Review 7.  DangER: protein ovERload. Targeting protein degradation to treat myeloma.

Authors:  Lauren I Aronson; Faith E Davies
Journal:  Haematologica       Date:  2012-05-11       Impact factor: 9.941

8.  HSF1 Is Essential for Myeloma Cell Survival and A Promising Therapeutic Target.

Authors:  Jacqueline H L Fok; Somaieh Hedayat; Lei Zhang; Lauren I Aronson; Fabio Mirabella; Charlotte Pawlyn; Michael D Bright; Christopher P Wardell; Jonathan J Keats; Emmanuel De Billy; Carl S Rye; Nicola E A Chessum; Keith Jones; Gareth J Morgan; Suzanne A Eccles; Paul Workman; Faith E Davies
Journal:  Clin Cancer Res       Date:  2018-02-01       Impact factor: 12.531

9.  Shock about heat shock in cancer.

Authors:  Emmanuel de Billy; Jon Travers; Paul Workman
Journal:  Oncotarget       Date:  2012-08

10.  Targeting HSF1 sensitizes cancer cells to HSP90 inhibition.

Authors:  Yaoyu Chen; Jinyun Chen; Alice Loo; Savina Jaeger; Linda Bagdasarian; Jianjun Yu; Franklin Chung; Joshua Korn; David Ruddy; Ribo Guo; Margaret E McLaughlin; Fei Feng; Ping Zhu; Frank Stegmeier; Raymond Pagliarini; Dale Porter; Wenlai Zhou
Journal:  Oncotarget       Date:  2013-06
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