Literature DB >> 19900740

Virucidal activity of 2 alcohol-based formulations proposed as hand rubs by the World Health Organization.

Jochen Steinmann1, Britta Becker, Birte Bischoff, Dajana Paulmann, Martina Friesland, Thomas Pietschmann, Jörg Steinmann, Eike Steinmann.   

Abstract

The virucidal activity of 2 hand rubs proposed by the World Health Organization was studied in a quantitative suspension test for chemical disinfectants and antiseptics in human medicine (EN 14476). These formulations are recommended if no hand rubs with declared microbiological activity are available in health care settings. Formulation I, based on ethanol, inactivated bovine viral diarrhea virus (BVDV), hepatitis C virus (HCV), adenovirus, and murine norovirus as a surrogate for human norovirus. Formulation II, based on isopropyl alcohol, was active only against adenovirus and enveloped viruses, such as BVDV and HCV. Both formulations failed to inactivate poliovirus by 4 log(10) steps within 300 seconds. Copyright 2010 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.

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Year:  2009        PMID： 19900740     DOI： 10.1016/j.ajic.2009.07.009

Source DB:  PubMed          Journal:  Am J Infect Control        ISSN： 0196-6553            Impact factor:   2.918


  9 in total

1.  Evaluation and clinical validation of an alcohol-based transport medium for preservation and inactivation of respiratory viruses.

Authors:  Kathy Luinstra; Astrid Petrich; Santina Castriciano; Mona Ackerman; Sylvia Chong; Susan Carruthers; Brenna Ammons; James B Mahony; Marek Smieja
Journal:  J Clin Microbiol       Date:  2011-04-20       Impact factor: 5.948

Review 2.  Ethanol is indispensable for virucidal hand antisepsis: memorandum from the alcohol-based hand rub (ABHR) Task Force, WHO Collaborating Centre on Patient Safety, and the Commission for Hospital Hygiene and Infection Prevention (KRINKO), Robert Koch Institute, Berlin, Germany.

Authors:  Axel Kramer; Mardjan Arvand; Bärbel Christiansen; Stephanie Dancer; Maren Eggers; Martin Exner; Dieter Müller; Nico T Mutters; Ingeborg Schwebke; Didier Pittet
Journal:  Antimicrob Resist Infect Control       Date:  2022-07-06       Impact factor: 6.454

3.  Delayed norovirus epidemic in the 2009-2010 season in Japan: potential relationship with intensive hand sanitizer use for pandemic influenza.

Authors:  S Inaida; Y Shobugawa; S Matsuno; R Saito; H Suzuki
Journal:  Epidemiol Infect       Date:  2016-06-15       Impact factor: 4.434

4.  Virucidal activity of Formulation I of the World Health Organization's alcohol-based handrubs: impact of changes in key ingredient levels and test parameters.

Authors:  Jochen Steinmann; Britta Becker; Birte Bischoff; Thomas Magulski; Joerg Steinmann; Eike Steinmann
Journal:  Antimicrob Resist Infect Control       Date:  2013-12-12       Impact factor: 4.887

5.  Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses.

Authors:  Anindya Siddharta; Stephanie Pfaender; Nathalie Jane Vielle; Ronald Dijkman; Martina Friesland; Britta Becker; Jaewon Yang; Michael Engelmann; Daniel Todt; Marc P Windisch; Florian H Brill; Joerg Steinmann; Jochen Steinmann; Stephan Becker; Marco P Alves; Thomas Pietschmann; Markus Eickmann; Volker Thiel; Eike Steinmann
Journal:  J Infect Dis       Date:  2017-03-15       Impact factor: 5.226

6.  Susceptibility of Chikungunya Virus to Inactivation by Heat and Commercially and World Health Organization-Recommended Biocides.

Authors:  Sergej Franz; Martina Friesland; Vânia Passos; Daniel Todt; Graham Simmons; Christine Goffinet; Eike Steinmann
Journal:  J Infect Dis       Date:  2018-09-22       Impact factor: 5.226

7.  Efficacy of hand rubs with a low alcohol concentration listed as effective by a national hospital hygiene society in Europe.

Authors:  Günter Kampf; Christiane Ostermeyer; Heinz-Peter Werner; Miranda Suchomel
Journal:  Antimicrob Resist Infect Control       Date:  2013-06-12       Impact factor: 4.887

Review 8.  Efficacy of ethanol against viruses in hand disinfection.

Authors:  G Kampf
Journal:  J Hosp Infect       Date:  2017-09-05       Impact factor: 3.926

Review 9.  [Disinfectants during the COVID-19 pandemic: a challenge].

Authors:  Maren Eggers; Anna Baumann; Nils Lilienthal; Eike Steinmann; Jochen Steinmann; Nils-Olaf Hübner; Holger F Rabenau; Viola Weinheimer; Ingeborg Schwebke
Journal:  Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz       Date:  2021-12-08       Impact factor: 1.513
  9 in total

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