Literature DB >> 19900686

Bioactive jatrophane diterpenes from Euphorbia guyoniana.

Mohamed-Elamir F Hegazy1, Abou El-Hamd H Mohamed, Nobuwa Aoki, Toshitaka Ikeuchi, Emi Ohta, Shinji Ohta.   

Abstract

Chromatographic investigation of the methylenechloride/methanol extract of the aerial parts of Euphorbia guyoniana afforded two jatrophane diterpenes, designated guyonianins E and F, in addition to a known jatrophane diterpene. The structures of the compounds were determined by comprehensive NMR analyses, including DEPT, COSY, HMQC, HMBC, NOESY and HRMS. These compounds exhibited cytotoxicity against human embryonic kidney 293 (HEK293) cells with IC(50) values of 35-100 microM. 2009 Elsevier Ltd. All rights reserved.

Entities:  

Mesh:

Substances:

Year:  2009        PMID: 19900686     DOI: 10.1016/j.phytochem.2009.10.003

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  2 in total

1.  Heliosterpenoids A and B, two Novel Jatrophane-Derived Diterpenoids with a 5/6/4/6 Ring System from Euphorbia helioscopia.

Authors:  Zhen-Peng Mai; Gang Ni; Yan-Fei Liu; Li Li; Guo-Ru Shi; Xin Wang; Jia-Yuan Li; De-Quan Yu
Journal:  Sci Rep       Date:  2017-07-07       Impact factor: 4.379

Review 2.  Jatrophane and rearranged jatrophane-type diterpenes: biogenesis, structure, isolation, biological activity and SARs (1984-2019).

Authors:  Maryam Fattahian; Mustafa Ghanadian; Zulfiqar Ali; Ikhlas A Khan
Journal:  Phytochem Rev       Date:  2020-04-13       Impact factor: 7.741

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.