| Literature DB >> 19900686 |
Mohamed-Elamir F Hegazy1, Abou El-Hamd H Mohamed, Nobuwa Aoki, Toshitaka Ikeuchi, Emi Ohta, Shinji Ohta.
Abstract
Chromatographic investigation of the methylenechloride/methanol extract of the aerial parts of Euphorbia guyoniana afforded two jatrophane diterpenes, designated guyonianins E and F, in addition to a known jatrophane diterpene. The structures of the compounds were determined by comprehensive NMR analyses, including DEPT, COSY, HMQC, HMBC, NOESY and HRMS. These compounds exhibited cytotoxicity against human embryonic kidney 293 (HEK293) cells with IC(50) values of 35-100 microM. 2009 Elsevier Ltd. All rights reserved.Entities:
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Year: 2009 PMID: 19900686 DOI: 10.1016/j.phytochem.2009.10.003
Source DB: PubMed Journal: Phytochemistry ISSN: 0031-9422 Impact factor: 4.072