Literature DB >> 19900381

[Fournier's gangrene. Descriptive analysis of 20 cases and literature review].

Raúl Montoya Chinchilla1, Emilio Izquierdo Morejon, Bogdan Nicolae Pietricicâ, Enrique Pellicer Franco, José Luis Aguayo Albasini, Bernardino Miñana López.   

Abstract

BACKGROUND: Fournier's gangrene is a necrotising fasciitis that usually affects the external genitalia and perineal area and may extend to the abdomen, lower limbs and chest. It hasa high fatality rate and must be treated aggressively within a few hours of being diagnosed. It is believed that debilitating diseases such as diabetes mellitus or obesity are conducive to its appearance. A perianal abscess is the most common trigger.
OBJECTIVE: To conduct a thorough descriptive analysis of risk factors and predisposing conditions for Fournier's gangrene based on our institution's experience over the past 12 years and reveal the mortality rate for those factors as well as the average number of reoperations performed.
MATERIAL AND METHODS: This observational retrospective study examines 20 patients, according to clinical inclusion criteria, who were diagnosed with Fournier's gangrene, and treated in J.M. Morales Meseguer Hospital between 1997 and 2008.
RESULTS: The vast majority of patients reviewed were males, with an average age of 61 years. All patients had a significant history of organic pathology, particularly diabetes mellitus. The average hospital stay was 25.7 days. 2 patients died, and the overall mortality rate was 10%.
CONCLUSIONS: Fournier's gangrene is an entity that can be lethal and it is favoured by several debilitating factors. It is triggered by a urogenital or perirectal disease that has not been treated properly. Because of its poor prognosis, early diagnosis and an appropriate early and aggressive multidisciplinary intervention are essential for proper recovery.

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Year:  2009        PMID: 19900381     DOI: 10.1016/s0210-4806(09)72875-x

Source DB:  PubMed          Journal:  Actas Urol Esp        ISSN: 0210-4806            Impact factor:   0.994


  6 in total

1.  [Affections of the external genitalia and their management].

Authors:  R Rossi; H Rübben
Journal:  Urologe A       Date:  2010-12       Impact factor: 0.639

Review 2.  Fournier's gangrene: A retrospective analysis of 26 cases in a Canadian hospital and literature review.

Authors:  Michael McCormack; Anne Sophie Valiquette; Salima Ismail
Journal:  Can Urol Assoc J       Date:  2015 May-Jun       Impact factor: 1.862

3.  Infections in patients with diabetes mellitus: A review of pathogenesis.

Authors:  Juliana Casqueiro; Janine Casqueiro; Cresio Alves
Journal:  Indian J Endocrinol Metab       Date:  2012-03

4.  The clinical presentation and early outcomes of necrotizing fasciitis in a Ugandan Tertiary Hospital--a prospective study.

Authors:  John Magala; Patson Makobore; Timothy Makumbi; Sam Kaggwa; Edris Kalanzi; Moses Galukande
Journal:  BMC Res Notes       Date:  2014-07-28

5.  The evaluation of microbiology and prognosis of fournier's gangrene in past five years.

Authors:  Lap-Ming Tang; Yu-Jang Su; Yen-Chun Lai
Journal:  Springerplus       Date:  2015-01-13

6.  Fournier's gangrene: prospective study of 34 patients in South Indian population and treatment strategies.

Authors:  Vigneswara Srinivasan Sockkalingam; Elankumar Subburayan; Elango Velu; Sujith Tumkur Rajashekar; Anusha Mruthyunjaya Swamy
Journal:  Pan Afr Med J       Date:  2018-10-12
  6 in total

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