Literature DB >> 19899849

Genetic and environmental influences on disordered eating: An adoption study.

Kelly L Klump1, Jessica L Suisman, S Alexandra Burt, Matt McGue, William G Iacono.   

Abstract

Twin studies indicate significant genetic, but little shared environmental, influences on eating disorders. However, critics argue that study limitations constrain the conclusions that can be drawn. Adoption studies avoid many of these limitations, but to date, no adoption studies of eating pathology have been conducted. The current study was the first adoption study to examine genetic/environmental effects for disordered eating. Participants included 123 adopted and 56 biological female sibling pairs. Disordered eating (i.e., overall eating pathology, body dissatisfaction, weight preoccupation, binge eating) was assessed with the Minnesota Eating Behaviors Survey (Klump, McGue, & Iacono, 2000; von Ranson, Klump, Iacono, & McGue, 2005). Biometric model fitting indicated significant genetic influences (59%-82%) on all forms of disordered eating, with nonshared environmental factors accounting for the remaining variance. Shared environmental factors did not contribute significantly to any disordered eating symptom. Our findings bolster those from twin studies and provide critical evidence of significant genetic effects on disordered eating symptoms. PsycINFO Database Record 2009 APA, all rights reserved.

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Year:  2009        PMID: 19899849      PMCID: PMC2805262          DOI: 10.1037/a0017204

Source DB:  PubMed          Journal:  J Abnorm Psychol        ISSN: 0021-843X


  50 in total

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2.  Do weight and shape concerns exhibit genetic effects? Investigating discrepant findings.

Authors:  Alexia Spanos; S Alexandra Burt; Kelly L Klump
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3.  Rethinking environmental contributions to child and adolescent psychopathology: a meta-analysis of shared environmental influences.

Authors:  S Alexandra Burt
Journal:  Psychol Bull       Date:  2009-07       Impact factor: 17.737

4.  Heritability of binge-eating and broadly defined bulimia nervosa.

Authors:  C M Bulik; P F Sullivan; K S Kendler
Journal:  Biol Psychiatry       Date:  1998-12-15       Impact factor: 13.382

5.  The power of the classical twin study.

Authors:  N G Martin; L J Eaves; M J Kearsey; P Davies
Journal:  Heredity (Edinb)       Date:  1978-02       Impact factor: 3.821

6.  Genetic influences on eating attitudes in a normal female twin population.

Authors:  J Rutherford; P McGuffin; R J Katz; R M Murray
Journal:  Psychol Med       Date:  1993-05       Impact factor: 7.723

7.  The developmental association between eating disorders symptoms and symptoms of depression and anxiety in juvenile twin girls.

Authors:  Judy L Silberg; Cynthia M Bulik
Journal:  J Child Psychol Psychiatry       Date:  2005-12       Impact factor: 8.982

8.  The genetic epidemiology of bulimia nervosa.

Authors:  K S Kendler; C MacLean; M Neale; R Kessler; A Heath; L Eaves
Journal:  Am J Psychiatry       Date:  1991-12       Impact factor: 18.112

9.  Heritability of bipolar spectrum disorders. Unity or heterogeneity?

Authors:  Jack Edvardsen; Svenn Torgersen; Espen Røysamb; Sissel Lygren; Ingunn Skre; Sidsel Onstad; Per Anders Oien
Journal:  J Affect Disord       Date:  2007-08-09       Impact factor: 4.839

10.  Changes in genetic and environmental influences on disordered eating across adolescence: a longitudinal twin study.

Authors:  Kelly L Klump; S Alexandra Burt; Matt McGue; William G Iacono
Journal:  Arch Gen Psychiatry       Date:  2007-12
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  20 in total

Review 1.  A review of family therapy as an effective intervention for anorexia nervosa in adolescents.

Authors:  Amanda Smith; Catherine Cook-Cottone
Journal:  J Clin Psychol Med Settings       Date:  2011-12

2.  Parental divorce and disordered eating: an investigation of a gene-environment interaction.

Authors:  Jessica L Suisman; S Alexandra Burt; Matt McGue; William G Iacono; Kelly L Klump
Journal:  Int J Eat Disord       Date:  2010-11-09       Impact factor: 4.861

Review 3.  Role of eating disorders-related polymorphisms in obesity pathophysiology.

Authors:  Carolina Ferreira Nicoletti; Heitor Bernardes Pereira Delfino; Flávia Campos Ferreira; Marcela Augusta de Souza Pinhel; Carla Barbosa Nonino
Journal:  Rev Endocr Metab Disord       Date:  2019-03       Impact factor: 6.514

4.  Genetics and Epigenetics of Eating Disorders.

Authors:  Zeynep Yilmaz; J Andrew Hardaway; Cynthia M Bulik
Journal:  Adv Genomics Genet       Date:  2015-03-10

Review 5.  The heritability of eating disorders: methods and current findings.

Authors:  Laura M Thornton; Suzanne E Mazzeo; Cynthia M Bulik
Journal:  Curr Top Behav Neurosci       Date:  2011

6.  Genetic and environmental influences on thin-ideal internalization.

Authors:  Jessica L Suisman; Shannon M O'Connor; Steffanie Sperry; J Kevin Thompson; Pamela K Keel; S Alexandra Burt; Michael Neale; Steven Boker; Cheryl Sisk; Kelly L Klump
Journal:  Int J Eat Disord       Date:  2012-10-03       Impact factor: 4.861

7.  The possible influence of impulsivity and dietary restraint on associations between serotonin genes and binge eating.

Authors:  Sarah E Racine; Kristen M Culbert; Christine L Larson; Kelly L Klump
Journal:  J Psychiatr Res       Date:  2009-06-02       Impact factor: 4.791

8.  Genetics and Epigenetics of Eating Disorders.

Authors:  Stephanie Zerwas; Cynthia M Bulik
Journal:  Psychiatr Ann       Date:  2011-11

9.  Bipolar disorder with comorbid binge eating history: a genome-wide association study implicates APOB.

Authors:  Stacey J Winham; Alfredo B Cuellar-Barboza; Susan L McElroy; Alfredo Oliveros; Scott Crow; Colin L Colby; Doo-Sup Choi; Mohit Chauhan; Mark A Frye; Joanna M Biernacka
Journal:  J Affect Disord       Date:  2014-04-19       Impact factor: 4.839

10.  Differences in genetic and environmental influences on body weight and shape concerns across pubertal development in females.

Authors:  Shannon M O'Connor; Kristen M Culbert; Laura A Mayhall; S Alexandra Burt; Kelly L Klump
Journal:  J Psychiatr Res       Date:  2019-11-08       Impact factor: 4.791

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