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Literature DB >> 19899085

Cholesterol secosterol adduction inhibits the misfolding of a mutant prion protein fragment that induces neurodegeneration.

Johanna C Scheinost¹, Daniel P Witter, Grant E Boldt, John Offer, Paul Wentworth.

Abstract

Entities: Chemical Disease Gene Mutation Species

Mesh：

Substances：

Year: 2009 PMID： 19899085 PMCID： PMC2837945 DOI： 10.1002/anie.200904524

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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24 in total

1. A synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice.

Authors: K Kaneko; H L Ball; H Wille; H Zhang; D Groth; M Torchia; P Tremblay; J Safar; S B Prusiner; S J DeArmond; M A Baldwin; F E Cohen
Journal: J Mol Biol Date: 2000-01-28 Impact factor: 5.469

2. Acquisition of protease resistance by prion proteins in scrapie-infected cells does not require asparagine-linked glycosylation.

Authors: A Taraboulos; M Rogers; D R Borchelt; M P McKinley; M Scott; D Serban; S B Prusiner
Journal: Proc Natl Acad Sci U S A Date: 1990-11 Impact factor: 11.205

Review 3. The human spongiform encephalopathies: kuru, Creutzfeldt-Jakob disease, and the Gerstmann-Sträussler-Scheinker syndrome.

Authors: P Brown; D C Gajdusek
Journal: Curr Top Microbiol Immunol Date: 1991 Impact factor: 4.291

Review 4. Molecular biology of prion diseases.

Authors: S B Prusiner
Journal: Science Date: 1991-06-14 Impact factor: 47.728

5. Solid-state NMR studies of the secondary structure of a mutant prion protein fragment of 55 residues that induces neurodegeneration.

Authors: D D Laws; H M Bitter; K Liu; H L Ball; K Kaneko; H Wille; F E Cohen; S B Prusiner; A Pines; D E Wemmer
Journal: Proc Natl Acad Sci U S A Date: 2001-09-18 Impact factor: 11.205

6. Chemoprophylaxis of scrapie in mice.

Authors: H Diringer; B Ehlers
Journal: J Gen Virol Date: 1991-02 Impact factor: 3.891

7. Potent inhibition of scrapie-associated PrP accumulation by congo red.

Authors: B Caughey; R E Race
Journal: J Neurochem Date: 1992-08 Impact factor: 5.372

8. Lipid-derived aldehydes accelerate light chain amyloid and amorphous aggregation.

Authors: Jorge Nieva; Asher Shafton; Laurence J Altobell; Sangeetha Tripuraneni; Joseph K Rogel; Anita D Wentworth; Richard A Lerner; Paul Wentworth
Journal: Biochemistry Date: 2008-06-26 Impact factor: 3.162

9. Evidence for ozone formation in human atherosclerotic arteries.

Authors: Paul Wentworth; Jorge Nieva; Cindy Takeuchi; Roger Galve; Anita D Wentworth; Ralph B Dilley; Giacomo A DeLaria; Alan Saven; Bernard M Babior; Kim D Janda; Albert Eschenmoser; Richard A Lerner
Journal: Science Date: 2003-11-07 Impact factor: 47.728

10. Metabolite-initiated protein misfolding may trigger Alzheimer's disease.

Authors: Qinghai Zhang; Evan T Powers; Jorge Nieva; Mary E Huff; Maria A Dendle; Jan Bieschke; Charles G Glabe; Albert Eschenmoser; Paul Wentworth; Richard A Lerner; Jeffery W Kelly
Journal: Proc Natl Acad Sci U S A Date: 2004-03-19 Impact factor: 11.205

6 in total

1. Adduction of cholesterol 5,6-secosterol aldehyde to membrane-bound myelin basic protein exposes an immunodominant epitope.

Authors: Natalie K Cygan; Johanna C Scheinost; Terry D Butters; Paul Wentworth
Journal: Biochemistry Date: 2011-02-28 Impact factor: 3.162

Review 5. A Photosensitized Singlet Oxygen (¹O₂) Toolbox for Bio-Organic Applications: Tailoring ¹O₂ Generation for DNA and Protein Labelling, Targeting and Biosensing.

Authors: Dorien Aerssens; Enrico Cadoni; Laure Tack; Annemieke Madder
Journal: Molecules Date: 2022-01-25 Impact factor: 4.411

Review 6. Biochemical properties of cholesterol aldehyde secosterol and its derivatives.

Authors: Noriyuki Miyoshi
Journal: J Clin Biochem Nutr Date: 2018-02-07 Impact factor: 3.114

6 in total

Cholesterol secosterol adduction inhibits the misfolding of a mutant prion protein fragment that induces neurodegeneration.

1. A synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice.

2. Acquisition of protease resistance by prion proteins in scrapie-infected cells does not require asparagine-linked glycosylation.

Review 3. The human spongiform encephalopathies: kuru, Creutzfeldt-Jakob disease, and the Gerstmann-Sträussler-Scheinker syndrome.

Review 4. Molecular biology of prion diseases.

5. Solid-state NMR studies of the secondary structure of a mutant prion protein fragment of 55 residues that induces neurodegeneration.

6. Chemoprophylaxis of scrapie in mice.

7. Potent inhibition of scrapie-associated PrP accumulation by congo red.

8. Lipid-derived aldehydes accelerate light chain amyloid and amorphous aggregation.

9. Evidence for ozone formation in human atherosclerotic arteries.

10. Metabolite-initiated protein misfolding may trigger Alzheimer's disease.

1. Adduction of cholesterol 5,6-secosterol aldehyde to membrane-bound myelin basic protein exposes an immunodominant epitope.

2. Cholesterol secosterol aldehydes induce amyloidogenesis and dysfunction of wild-type tumor protein p53.

Review 3. New views on cellular uptake and trafficking of manufactured nanoparticles.

4. Reactive Sterol Electrophiles: Mechanisms of Formation and Reactions with Proteins and Amino Acid Nucleophiles.

Review 5. A Photosensitized Singlet Oxygen (¹O₂) Toolbox for Bio-Organic Applications: Tailoring ¹O₂ Generation for DNA and Protein Labelling, Targeting and Biosensing.

Review 6. Biochemical properties of cholesterol aldehyde secosterol and its derivatives.

Review 3. The human spongiform encephalopathies: kuru, Creutzfeldt-Jakob disease, and the Gerstmann-Sträussler-Scheinker syndrome.

Review 4. Molecular biology of prion diseases.

Review 3. New views on cellular uptake and trafficking of manufactured nanoparticles.

Review 5. A Photosensitized Singlet Oxygen (1O2) Toolbox for Bio-Organic Applications: Tailoring 1O2 Generation for DNA and Protein Labelling, Targeting and Biosensing.

Review 6. Biochemical properties of cholesterol aldehyde secosterol and its derivatives.

Review 5. A Photosensitized Singlet Oxygen (¹O₂) Toolbox for Bio-Organic Applications: Tailoring ¹O₂ Generation for DNA and Protein Labelling, Targeting and Biosensing.