Literature DB >> 19898701

Thrombolysis versus primary percutaneous coronary intervention for ST elevation myocardial infarctions at Chilliwack General Hospital.

S P Janda1, N Tan.   

Abstract

BACKGROUND: Studies have shown that primary percutaneous coronary intervention (PCI), when performed by an experienced operator immediately after admission in a high-volume tertiary care centre, results in lower in-hospital mortality, and decreased risk of reinfarction and stroke. Furthermore, for those communities without a PCI centre, transport of patients to a PCI centre within 90 min is superior to thrombolysis. Chilliwack General Hospital (CGH, Chilliwack, British Columbia) has a unique situation - the travel time to the nearest coronary catheterization centre (Royal Columbian Hospital, New Westminster, British Columbia) is between 60 min and 120 min.
OBJECTIVES: To compare access to and use of thrombolysis versus PCI in individuals with ST elevation myocardial infarctions (STEMIs) at CGH.
METHODS: A retrospective chart review was conducted on patients who presented to the emergency department at CGH with STEMIs between January 1, 2004, and December 31, 2005. Of the 67 patients who had a STEMI during this time period, 40 patients met inclusion criteria, of whom, 32 received thrombolytics and eight received PCI.
RESULTS: The average door-to-thrombolysis time was 46 min (95% CI 32 min to 60 min). A door-to-thrombolysis time of less then 30 min was achieved in 15 of 32 patients (47%). The average door-to-balloon time was 186 min (95% CI 166 min to 206 min). A door-to-balloon time of less than 90 min was not achieved in any of the eight patients who received PCI.
CONCLUSIONS: CGH did not meet the American Heart Association guidelines for a door-to-balloon time of less than 90 min.

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Year:  2009        PMID: 19898701      PMCID: PMC2776568          DOI: 10.1016/s0828-282x(09)70165-5

Source DB:  PubMed          Journal:  Can J Cardiol        ISSN: 0828-282X            Impact factor:   5.223


  18 in total

1.  Percutaneous coronary intervention versus fibrinolytic therapy in acute myocardial infarction: is timing (almost) everything?

Authors:  Brahmajee K Nallamothu; Eric R Bates
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2.  Delayed hospital presentation in patients who have had acute myocardial infarction.

Authors:  J H Gurwitz; T J McLaughlin; D J Willison; E Guadagnoli; P J Hauptman; X Gao; S B Soumerai
Journal:  Ann Intern Med       Date:  1997-04-15       Impact factor: 25.391

3.  A randomized trial of transfer for primary angioplasty versus on-site thrombolysis in patients with high-risk myocardial infarction: the Air Primary Angioplasty in Myocardial Infarction study.

Authors:  Cindy L Grines; Donald R Westerhausen; Lorelei L Grines; J Timothy Hanlon; Timothy L Logemann; Matti Niemela; W Douglas Weaver; Marianne Graham; Judith Boura; William W O'Neill; Carlos Balestrini
Journal:  J Am Coll Cardiol       Date:  2002-06-05       Impact factor: 24.094

4.  Multicentre randomized trial comparing transport to primary angioplasty vs immediate thrombolysis vs combined strategy for patients with acute myocardial infarction presenting to a community hospital without a catheterization laboratory. The PRAGUE study.

Authors:  P Widimský; L Groch; M Zelízko; M Aschermann; F Bednár; H Suryapranata
Journal:  Eur Heart J       Date:  2000-05       Impact factor: 29.983

5.  Early thrombolytic treatment in acute myocardial infarction: reappraisal of the golden hour.

Authors:  E Boersma; A C Maas; J W Deckers; M L Simoons
Journal:  Lancet       Date:  1996-09-21       Impact factor: 79.321

6.  A comparison of coronary angioplasty with fibrinolytic therapy in acute myocardial infarction.

Authors:  Henning R Andersen; Torsten T Nielsen; Klaus Rasmussen; Leif Thuesen; Henning Kelbaek; Per Thayssen; Ulrik Abildgaard; Flemming Pedersen; Jan K Madsen; Peer Grande; Anton B Villadsen; Lars R Krusell; Torben Haghfelt; Preben Lomholt; Steen E Husted; Else Vigholt; Henrik K Kjaergard; Leif Spange Mortensen
Journal:  N Engl J Med       Date:  2003-08-21       Impact factor: 91.245

7.  A comparison of immediate coronary angioplasty with intravenous streptokinase in acute myocardial infarction.

Authors:  F Zijlstra; M J de Boer; J C Hoorntje; S Reiffers; J H Reiber; H Suryapranata
Journal:  N Engl J Med       Date:  1993-03-11       Impact factor: 91.245

8.  A comparison of immediate angioplasty with thrombolytic therapy for acute myocardial infarction. The Primary Angioplasty in Myocardial Infarction Study Group.

Authors:  C L Grines; K F Browne; J Marco; D Rothbaum; G W Stone; J O'Keefe; P Overlie; B Donohue; N Chelliah; G C Timmis
Journal:  N Engl J Med       Date:  1993-03-11       Impact factor: 91.245

9.  Immediate angioplasty compared with the administration of a thrombolytic agent followed by conservative treatment for myocardial infarction. The Mayo Coronary Care Unit and Catheterization Laboratory Groups.

Authors:  R J Gibbons; D R Holmes; G S Reeder; K R Bailey; M R Hopfenspirger; B J Gersh
Journal:  N Engl J Med       Date:  1993-03-11       Impact factor: 91.245

Review 10.  Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials.

Authors:  Ellen C Keeley; Judith A Boura; Cindy L Grines
Journal:  Lancet       Date:  2003-01-04       Impact factor: 79.321

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  4 in total

1.  Developing a system of care for emergency revascularization in acute myocardial infarction.

Authors:  Albert W Chan; Gerald J Simkus
Journal:  Can J Cardiol       Date:  2010-05       Impact factor: 5.223

2.  Creating synergy in our health system: The challenges of primary angioplasty.

Authors:  F Charbonneau
Journal:  Can J Cardiol       Date:  2009-11       Impact factor: 5.223

3.  Treatment delay in ST elevation myocardial infarction care in a community hospital -- a cautionary tale.

Authors:  J Ducas; W J Cantor
Journal:  Can J Cardiol       Date:  2009-11       Impact factor: 5.223

4.  Does Frequency of ST-Segment Elevation Myocardial Infarction Presentation Impact Quality of Care?

Authors:  Alex N Mazurek; Paul R Atkinson; Jaroslav Hubacek; Mark McGraw; Sohrab Lutchmedial
Journal:  Cureus       Date:  2017-11-26
  4 in total

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