Literature DB >> 19897704

A sympathetic model of L-type Ca2+ channel-triggered arrhythmias.

Jabe M Best, Timothy J Kamp.   

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Year:  2009        PMID: 19897704      PMCID: PMC2806129          DOI: 10.1152/ajpheart.01044.2009

Source DB:  PubMed          Journal:  Am J Physiol Heart Circ Physiol        ISSN: 0363-6135            Impact factor:   4.733


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Authors:  T J Kamp; J W Hell
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Review 2.  Cardiac excitation-contraction coupling.

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4.  Early afterdepolarizations: mechanism of induction and block. A role for L-type Ca2+ current.

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5.  Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations.

Authors:  Igor Splawski; Katherine W Timothy; Niels Decher; Pradeep Kumar; Frank B Sachse; Alan H Beggs; Michael C Sanguinetti; Mark T Keating
Journal:  Proc Natl Acad Sci U S A       Date:  2005-04-29       Impact factor: 11.205

6.  Kinetic properties of the cardiac L-type Ca2+ channel and its role in myocyte electrophysiology: a theoretical investigation.

Authors:  Gregory M Faber; Jonathan Silva; Leonid Livshitz; Yoram Rudy
Journal:  Biophys J       Date:  2006-12-08       Impact factor: 4.033

7.  Cyclosporin and Timothy syndrome increase mode 2 gating of CaV1.2 calcium channels through aberrant phosphorylation of S6 helices.

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8.  Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism.

Authors:  Igor Splawski; Katherine W Timothy; Leah M Sharpe; Niels Decher; Pradeep Kumar; Raffaella Bloise; Carlo Napolitano; Peter J Schwartz; Robert M Joseph; Karen Condouris; Helen Tager-Flusberg; Silvia G Priori; Michael C Sanguinetti; Mark T Keating
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9.  Cellular basis for the electrocardiographic and arrhythmic manifestations of Timothy syndrome: effects of ranolazine.

Authors:  Serge Sicouri; Katherine W Timothy; Andrew C Zygmunt; Aaron Glass; Robert J Goodrow; Luiz Belardinelli; Charles Antzelevitch
Journal:  Heart Rhythm       Date:  2007-01-07       Impact factor: 6.343

10.  A dynamic model of the cardiac ventricular action potential. II. Afterdepolarizations, triggered activity, and potentiation.

Authors:  C H Luo; Y Rudy
Journal:  Circ Res       Date:  1994-06       Impact factor: 17.367

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2.  Computational Cardiac Modeling Reveals Mechanisms of Ventricular Arrhythmogenesis in Long QT Syndrome Type 8: CACNA1C R858H Mutation Linked to Ventricular Fibrillation.

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3.  Pro-arrhythmogenic effects of CACNA1C G1911R mutation in human ventricular tachycardia: insights from cardiac multi-scale models.

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