Literature DB >> 1989727

High-performance liquid chromatography as a diagnostic tool in prolonged neuromuscular blockade.

D Mangar1, P B Kane.   

Abstract

We report the use of high-performance liquid chromatography (HPLC) to identify the cause of prolonged neuromuscular blockade in a child who had received 2 mg.kg-1 of succinylcholine. Upon analysis by HPLC the syringe was found to contain succinylcholine (10 mg.ml-1) and also atracurium (5 mg.ml-1), so that a diagnosis was established. In situations where medication errors are suspected, we recommend saving syringe contents for analysis for confirmation of the agent.

Entities:  

Mesh:

Substances:

Year:  1991        PMID: 1989727     DOI: 10.1007/BF03009171

Source DB:  PubMed          Journal:  Can J Anaesth        ISSN: 0832-610X            Impact factor:   5.063


  4 in total

1.  Human misadventure in anaesthesia.

Authors:  J E Utting; T C Gray; F C Shelley
Journal:  Can Anaesth Soc J       Date:  1979-11

2.  Critical incidents associated with intraoperative exchanges of anesthesia personnel.

Authors:  J B Cooper; C D Long; R S Newbower; J H Philip
Journal:  Anesthesiology       Date:  1982-06       Impact factor: 7.892

Review 3.  Plasma cholinesterase variants and the anaesthetist.

Authors:  M Whittaker
Journal:  Anaesthesia       Date:  1980-02       Impact factor: 6.955

4.  Quantitation of D-tubocurarine in human plasma using high-performance liquid chromatography.

Authors:  A Meulemans; J Mohler; D Henzel; P Duvaldestin
Journal:  J Chromatogr       Date:  1981-11-13
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.