Literature DB >> 19896059

Arthroscopic implantation of a matrix to cover large chondral defect during microfracture.

Thore Zantop1, Wolf Petersen.   

Abstract

Microfracturing techniques have been reported to be successful cartilage-restoring treatment options in defects of smaller sizes. The success may be limited by the size of the defect and the shoulder of the intact surrounding cartilage. We report a new technique using a 3-dimensional matrix to cover large cartilage defects during microfracture healing. In contrast to autologous chondrocyte implantation techniques, this technique is a 1-stage procedure. The defect cover consists of a resorbable polymer felt and sodium hyaluronan to induce hemostasis and to protect the underlying tissue. After conventional microfracture, the defect size is determined with an intra-articular measuring device, and the matrix is sized and introduced with an arthroscopic grasp. Depending on the size of the defect, the 3-dimensional matrix is fixed with 1 or 2 biodegradable pins perpendicular to the surface. The combination of the common microfracture technique with the implantation of the matrix leads to complete defect filling with cartilaginous repair tissue and therefore improves cartilage regeneration in the defect. We conclude that the introduced technique may be helpful in large cartilage defects combining the benefit of microfracturing and avoidance of the increased morbidity of matrix-associated autologous chondrocyte implantation.

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Year:  2009        PMID: 19896059     DOI: 10.1016/j.arthro.2009.04.077

Source DB:  PubMed          Journal:  Arthroscopy        ISSN: 0749-8063            Impact factor:   4.772


  23 in total

1.  Repair mechanism of osteochondral defect promoted by bioengineered chondrocyte sheet.

Authors:  Ryo Shimizu; Naosuke Kamei; Nobuo Adachi; Michio Hamanishi; Goki Kamei; Elhussein Elbadry Mahmoud; Tomohiro Nakano; Takanori Iwata; Masayuki Yamato; Teruo Okano; Mitsuo Ochi
Journal:  Tissue Eng Part A       Date:  2014-12-29       Impact factor: 3.845

2.  The combination of microfracture and a cell-free polymer-based implant immersed with autologous serum for cartilage defect coverage.

Authors:  A A M Dhollander; P C M Verdonk; S Lambrecht; K F Almqvist; D Elewaut; G Verbruggen; R Verdonk
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-11-09       Impact factor: 4.342

3.  Updates in biological therapies for knee injuries: full thickness cartilage defect.

Authors:  Alexandre Pedro Nicolini; Rogerio Teixeira Carvalho; Bruno Dragone; Mario Lenza; Moises Cohen; Mario Ferretti
Journal:  Curr Rev Musculoskelet Med       Date:  2014-09

4.  Bioactive factors in platelet-rich plasma obtained by apheresis.

Authors:  Jan Philipp Krüger; Undine Freymannx; Samuel Vetterlein; Katja Neumann; Michaela Endres; Christian Kaps
Journal:  Transfus Med Hemother       Date:  2013-10-27       Impact factor: 3.747

5.  Cell-free repair of small cartilage defects in the Goettinger minipig: which defect size is possible?

Authors:  K Gavenis; U Schneider; U Maus; T Mumme; R Muller-Rath; Bernhard Schmidt-Rohlfing; S Andereya
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-12-28       Impact factor: 4.342

6.  A cell-free scaffold-based cartilage repair provides improved function hyaline-like repair at one year.

Authors:  Alberto Siclari; Gennaro Mascaro; Chiara Gentili; Ranieri Cancedda; Eugenio Boux
Journal:  Clin Orthop Relat Res       Date:  2011-10-01       Impact factor: 4.176

7.  [Arthroscopic options for regenerative treatment of cartilage defects in the shoulder].

Authors:  I J Banke; S Vogt; S Buchmann; A B Imhoff
Journal:  Orthopade       Date:  2011-01       Impact factor: 1.087

8.  Chondrogenic regeneration using bone marrow clots and a porous polycaprolactone-hydroxyapatite scaffold by three-dimensional printing.

Authors:  Qingqiang Yao; Bo Wei; Nancy Liu; Chenshuang Li; Yang Guo; Arya Nick Shamie; James Chen; Cheng Tang; Chengzhe Jin; Yan Xu; Xiuwu Bian; Xinli Zhang; Liming Wang
Journal:  Tissue Eng Part A       Date:  2015-04       Impact factor: 3.845

9.  Arthroscopic knee cartilage repair with covered microfracture and bone marrow concentrate.

Authors:  Antonio Gigante; Stefano Cecconi; Silvano Calcagno; Alberto Busilacchi; Davide Enea
Journal:  Arthrosc Tech       Date:  2012-09-14

10.  Cartilage repair in the knee with subchondral drilling augmented with a platelet-rich plasma-immersed polymer-based implant.

Authors:  Alberto Siclari; Gennaro Mascaro; Chiara Gentili; Christian Kaps; Ranieri Cancedda; Eugenio Boux
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2013-04-07       Impact factor: 4.342

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