Literature DB >> 19895830

Indirect mechanisms of carcinogenesis via downregulation of PTEN function.

Nick R Leslie1, Laura Spinelli, Priyanka Tibarewal, Georgios Zilidis, Nimmi Weerasinghe, Joseph C Lim, Helene Maccario, C Peter Downes.   

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Year:  2009        PMID: 19895830     DOI: 10.1016/j.advenzreg.2009.10.015

Source DB:  PubMed          Journal:  Adv Enzyme Regul        ISSN: 0065-2571


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  6 in total

1.  Ubiquitination of PTEN (phosphatase and tensin homolog) inhibits phosphatase activity and is enhanced by membrane targeting and hyperosmotic stress.

Authors:  Helene Maccario; Nevin M Perera; Alexander Gray; C Peter Downes; Nick R Leslie
Journal:  J Biol Chem       Date:  2010-02-22       Impact factor: 5.157

2.  HMGB1-Induced Cross Talk between PTEN and miRs 221/222 in Thyroid Cancer.

Authors:  S Mardente; E Mari; I Massimi; F Fico; A Faggioni; F Pulcinelli; A Antonaci; A Zicari
Journal:  Biomed Res Int       Date:  2015-05-27       Impact factor: 3.411

3.  Methylmercury, an environmental electrophile capable of activation and disruption of the Akt/CREB/Bcl-2 signal transduction pathway in SH-SY5Y cells.

Authors:  Takamitsu Unoki; Yumi Abiko; Takashi Toyama; Takashi Uehara; Koji Tsuboi; Motohiro Nishida; Toshiyuki Kaji; Yoshito Kumagai
Journal:  Sci Rep       Date:  2016-06-30       Impact factor: 4.379

4.  PTEN promoter methylation predicts 10-year prognosis in hormone receptor-positive early breast cancer patients who received adjuvant tamoxifen endocrine therapy.

Authors:  Yu Fan; Guiqin Xie; Zhu Wang; Yu Wang; Yanping Wang; Hong Zheng; Xiaorong Zhong
Journal:  Breast Cancer Res Treat       Date:  2022-01-03       Impact factor: 4.872

Review 5.  Phosphatase and Tensin Homologue: Novel Regulation by Developmental Signaling.

Authors:  Travis J Jerde
Journal:  J Signal Transduct       Date:  2015-08-03

Review 6.  Prognostic and Predictive Implications of PTEN in Breast Cancer: Unfulfilled Promises but Intriguing Perspectives.

Authors:  Luisa Carbognin; Federica Miglietta; Ida Paris; Maria Vittoria Dieci
Journal:  Cancers (Basel)       Date:  2019-09-19       Impact factor: 6.639

  6 in total

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