| Literature DB >> 19895799 |
Cátia S Branco1, Márcia E Garcez, Fábio F Pasqualotto, Bernardo Erdtman, Mirian Salvador.
Abstract
Cryopreservation of human semen can cause DNA damages, which compromise the fertilization and normal embryo development. The present study showed that the antioxidant resveratrol prevents these damages both in fertile and infertile men. The addition of ascorbic acid before cryopreservation can reduce DNA damages only in infertile men. Although further studies are needed, the present work showed that resveratrol could be considered in human cryopreservation procedures to avoid/minimize DNA damages and preserve sperm integrity. Copyright 2009 Elsevier Inc. All rights reserved.Entities:
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Year: 2009 PMID： 19895799 DOI： 10.1016/j.cryobiol.2009.10.012
Source DB: PubMed Journal: Cryobiology ISSN： 0011-2240 Impact factor: 2.487