Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Asymmetric total syntheses of (-)-renieramycin M and G and (-)-jorumycin using aziridine as a lynchpin.

Literature DB >> 19894720

Asymmetric total syntheses of (-)-renieramycin M and G and (-)-jorumycin using aziridine as a lynchpin.

Abstract

By exploring the triple reactivity of two aziridines and double nucleophilicity of two aromatics, convergent and versatile syntheses of the above four natural products were developed.

Entities: Chemical

Mesh：

Substances：

Year: 2009 PMID： 19894720 DOI： 10.1021/ol9024919

Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005

Keyword Cloud
Cited

7 in total

1. Concise total syntheses of (-)-jorunnamycin A and (-)-jorumycin enabled by asymmetric catalysis.

Authors: Eric R Welin; Aurapat Ngamnithiporn; Max Klatte; Guillaume Lapointe; Gerit M Pototschnig; Martina S J McDermott; Dylan Conklin; Christopher D Gilmore; Pamela M Tadross; Christopher K Haley; Kenji Negoro; Emil Glibstrup; Christian U Grünanger; Kevin M Allan; Scott C Virgil; Dennis J Slamon; Brian M Stoltz
Journal: Science Date: 2018-12-20 Impact factor: 47.728

2. Total Syntheses and Biological Evaluation of Both Enantiomers of Several Hydroxylated Dimeric Nuphar Alkaloids.

Authors: Alexander Korotkov; Hui Li; Charles W Chapman; Haoran Xue; John B MacMillan; Alan Eastman; Jimmy Wu
Journal: Angew Chem Int Ed Engl Date: 2015-07-16 Impact factor: 15.336

3. Late-Stage Diversification: A Motivating Force in Organic Synthesis.

Authors: Kelly E Kim; Alexia N Kim; Carter J McCormick; Brian M Stoltz
Journal: J Am Chem Soc Date: 2021-10-06 Impact factor: 16.383

Review 4. Recently confirmed apoptosis-inducing lead compounds isolated from marine sponge of potential relevance in cancer treatment.

Authors: Magbubah Essack; Vladimir B Bajic; John A C Archer
Journal: Mar Drugs Date: 2011-09-20 Impact factor: 6.085

Asymmetric total syntheses of (-)-renieramycin M and G and (-)-jorumycin using aziridine as a lynchpin.

1. Concise total syntheses of (-)-jorunnamycin A and (-)-jorumycin enabled by asymmetric catalysis.

2. Total Syntheses and Biological Evaluation of Both Enantiomers of Several Hydroxylated Dimeric Nuphar Alkaloids.

3. Late-Stage Diversification: A Motivating Force in Organic Synthesis.

Review 4. Recently confirmed apoptosis-inducing lead compounds isolated from marine sponge of potential relevance in cancer treatment.

Review 5. Synthetically important ring opening reactions by alkoxybenzenes and alkoxynaphthalenes.

Review 6. Marine Invertebrate Metabolites with Anticancer Activities: Solutions to the "Supply Problem".

Review 7. Preparation and Uses of Chlorinated Glycerol Derivatives.