| Literature DB >> 19894631 |
L M Baĭder, V P Reutov, A L Krushinskiĭ, V S Kuzenkov, E G Sorokina, V B Koshelev, O E Fadiukov, T T Zhymabaeva, T A Lozinova, L Kh Komissarova, V G Pinelis, N S Kositsin, Z V Kuropteva.
Abstract
The influence of hypoxia on nitric oxide formation in the blood of Krushinskii-Molodkina rats has been studied by electron paramagnetic resonance. It was found that nitric oxide synthesis in Krushinskii-Molodkina rats is increased compared with that in Wistar rats. A significant enhancement of the EPR signal of Hb-NO complexes in the animal blood was observed after hypoxia simulating the altitude of 5000 m above the sea level, in particular in the presence of sodium nitrite and the NO-synthase inhibitor L-nitroarginine. It was assumed that NO synthesis and nitro-/nitrite- reductase systems are activated under hypoxic conditions.Entities:
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Year: 2009 PMID： 19894631
Source DB: PubMed Journal: Biofizika ISSN： 0006-3029