Literature DB >> 19894384

Distribution and development of the TCM syndromes in psoriasis vulgaris.

Guang-Zhong Zhang1, Ju-Sheng Wang, Ping Wang, Chun-Yan Jiang, Bing-Xu Deng, Ping Li, Yi-Ming Zhao, Wa-Li Liu, Xing Qu, Wei-Wen Chen, Lin Zeng, Dong-Mei Zhou, Li-Yun Sun, Ruo-Yu Li.   

Abstract

OBJECTIVE: To study the distribution and development rules of the TCM syndromes in psoriasis vulgaris.
METHODS: Based on the clinical epidemiologic mass survey, the study was carried out by means of a status survey, multi-center and large-sample research. The data base was set up by EPIINFO6.0. The SPSS was used to do the statistical analyses in 2651 cases of psoriasis vulgaris to study the correlations among the distribution and development of the TCM syndromes, the stages of the disease, nationality, psoriasis history, family history, smoking history, alcohol drinking history, and severity of the disease.
RESULTS: The TCM syndromes in psoriasis vulgaris mainly include the blood-heat syndrome (53.8%), blood-dryness syndrome (27.4%), and blood-stasis syndrome (18.1%). Other syndromes were rarely seen, covering 0.6%. The concurrent syndromes mainly involve dampness, heat, blood stasis and toxin. The distribution differences of the main syndromes at different stages of the disease had statistical significance (P < 0.01). The syndrome distribution is not related with nationality and family history (P > 0.05), but it was closely related with the psoriasis history, smoking history, alcohol drinking history, and severity of the disease (P < 0.01).
CONCLUSION: At the initial stage, psoriasis vulgaris usually manifests itself as the blood-heat syndrome, and later it may be improved or turn into the blood-dryness or blood-stasis syndrome. Smoking, alcohol consumption, and severity of the disease may play a role in the syndrome's transformation.

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Year:  2009        PMID: 19894384     DOI: 10.1016/s0254-6272(09)60064-9

Source DB:  PubMed          Journal:  J Tradit Chin Med        ISSN: 0255-2922            Impact factor:   0.848


  5 in total

Review 1.  Oral herbal medicines for psoriasis: a review of clinical studies.

Authors:  Brian H May; Anthony L Zhang; Wenyu Zhou; Chuan-Jian Lu; Shiqiang Deng; Charlie C L Xue
Journal:  Chin J Integr Med       Date:  2012-04-02       Impact factor: 1.978

Review 2.  Immune Signatures in Patients with Psoriasis Vulgaris of Blood-Heat Syndrome: A Systematic Review and Meta-Analysis.

Authors:  Xin Li; Qing-Qing Xiao; Fu-Lun Li; Rong Xu; Bin Fan; Min-Feng Wu; Min Zhou; Su Li; Jie Chen; Shi-Guang Peng; Bin Li
Journal:  Evid Based Complement Alternat Med       Date:  2016-05-04       Impact factor: 2.629

3.  Efficacy of nano-modified Runji ointment in the treatment of mild and moderate psoriasis with blood dryness syndrome: a study protocol for a double-blind randomized controlled trial.

Authors:  Guanru Li; Liyun Sun; Yue Qiu; Yaquan Hou; Libo Du; Kaixuan Zhao; Jiali Qian; Jiuli Liu; Tengfei Ma
Journal:  Medicine (Baltimore)       Date:  2021-12-30       Impact factor: 1.889

4.  'Psoriasis 1' reduces psoriasis‑like skin inflammation by inhibiting the VDR‑mediated nuclear NF‑κB and STAT signaling pathways.

Authors:  Wen Sun; Yang Gao; Xianhua Yu; Yuan Yuan; Jun Yi; Zhen Zhang; Yuxing Cheng; Yong Li; Xing Peng; Xushan Cha
Journal:  Mol Med Rep       Date:  2018-07-09       Impact factor: 2.952

5.  Chinese Medicine for Psoriasis Vulgaris Based on Syndrome Pattern: A Network Pharmacological Study.

Authors:  Dongmei Wang; Chuanjian Lu; Jingjie Yu; Miaomiao Zhang; Wei Zhu; Jiangyong Gu
Journal:  Evid Based Complement Alternat Med       Date:  2020-04-28       Impact factor: 2.629

  5 in total

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