BACKGROUND: Obstructive sleep apnea (OSA) is related to increased systemic inflammation and arterial hypertension. We hypothesize that OSA is frequent in patients with acute hypertensive intracerebral hemorrhage (ICH) and is related to the perihematoma edema. METHODS: Thirty-two non-comatose patients with a hypertensive ICH underwent polysomnography in the acute phase. Perihematoma edema volume was measured on CT scans at admission, after 24 h (early control) and after 4-5 days (late control). The Spearman coefficient (r(s)) was used for correlations. RESULTS: OSA occurred in 19 (59.4%) patients. The apnea-hypopnea index was correlated with relative edema at admission CT (r(s) = 0.40; p = 0.031), early CT (r(s) = 0.46; p = 0.011) and at late CT (r(s) = 0.59; p = 0.006). CONCLUSIONS: OSA is highly frequent during the acute phase of hypertensive ICH and is related to perihematoma edema.
BACKGROUND: Obstructive sleep apnea (OSA) is related to increased systemic inflammation and arterial hypertension. We hypothesize that OSA is frequent in patients with acute hypertensive intracerebral hemorrhage (ICH) and is related to the perihematoma edema. METHODS: Thirty-two non-comatosepatients with a hypertensive ICH underwent polysomnography in the acute phase. Perihematoma edema volume was measured on CT scans at admission, after 24 h (early control) and after 4-5 days (late control). The Spearman coefficient (r(s)) was used for correlations. RESULTS: OSA occurred in 19 (59.4%) patients. The apnea-hypopnea index was correlated with relative edema at admission CT (r(s) = 0.40; p = 0.031), early CT (r(s) = 0.46; p = 0.011) and at late CT (r(s) = 0.59; p = 0.006). CONCLUSIONS: OSA is highly frequent during the acute phase of hypertensive ICH and is related to perihematoma edema.
Authors: Filip Alexiev; Anne-Kathrin Brill; Sebastian R Ott; Simone Duss; Markus Schmidt; Claudio L Bassetti Journal: J Thorac Dis Date: 2018-12 Impact factor: 2.895
Authors: Lynda D Lisabeth; Richard V Scheer; Chengwei Li; Erin Case; Ronald D Chervin; Darin B Zahuranec; Lewis B Morgenstern; Nelda M Garcia; Susan Tower; Devin L Brown Journal: Sleep Med Date: 2018-03-29 Impact factor: 3.492
Authors: Millene R Camilo; Regina M F Fernandes; Heidi H Sander; Fernando Nobre; Taiza Santos-Pontelli; Antonio C dos Santos; Draulio B de Araujo; João P Leite; Octavio M Pontes-Neto Journal: Clinics (Sao Paulo) Date: 2012-12 Impact factor: 2.365