| Literature DB >> 19889927 |
Pinggang Ming1, Jiaxin Yan, Simon Rayner, Shengli Meng, Gelin Xu, Qing Tang, Jie Wu, Jing Luo, Xiaoming Yang.
Abstract
To investigate the evolutionary dynamics of rabies virus (RABV) in China, we collected and sequenced 55 isolates sampled from 14 Chinese provinces over the last 40 years and performed a coalescent-based analysis of the G gene. This revealed that the RABV currently circulating in China is composed of three main groups. Bayesian coalescent analysis estimated the date of the most recent common ancestor for the current RABV Chinese strains to be 1412 (with a 95 % confidence interval of 1006-1736). The estimated mean substitution rate for the G gene sequences (3.961x10(-4) substitutions per site per year) was in accordance with previous reports for RABV.Entities:
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Year: 2009 PMID: 19889927 DOI: 10.1099/vir.0.016436-0
Source DB: PubMed Journal: J Gen Virol ISSN: 0022-1317 Impact factor: 3.891