Literature DB >> 19889007

Outcomes of childhood hemangiomas treated with the pulsed-dye laser with dynamic cooling: a retrospective chart analysis.

Carina Rizzo1, Lori Brightman, Anne M Chapas, Elizabeth K Hale, Julie L Cantatore-Francis, Leonard J Bernstein, Roy G Geronemus.   

Abstract

BACKGROUND: Laser treatment of childhood hemangiomas remains controversial. Previous studies have used outdated technology, resulting in a potential overrepresentation of adverse outcomes.
OBJECTIVE: To evaluate outcomes of hemangiomas treated with the most current laser technology.
METHODS: A retrospective chart analysis of 90 patients with a median age of 3.0 months and a total of 105 hemangiomas were enrolled over a 2.5-year period. All were treated with the 595-nm long-pulse pulsed-dye laser (LP-PDL) with dynamic epidermal cooling at 2- to 8-week intervals depending on the stage of growth. Exclusion criteria were previous laser, surgical, or corticosteroid treatment. Three reviewers assessed outcomes.
RESULTS: Near-complete or complete clearance in color were achieved for 85 (81%) and in thickness for 67 (64%) hemangiomas. There was no scarring or atrophy. Ulceration occurred in one case and resolved during treatment. Hyperpigmentation and hypopigmentation occurred in 4% and 14% of hemangiomas, respectively.
CONCLUSION: Early treatment of childhood hemangiomas with the 595-nm LP-PDL with dynamic cooling may reduce the proliferative phase and result in excellent rates of clearing and few adverse events.

Entities:  

Mesh:

Year:  2009        PMID: 19889007     DOI: 10.1111/j.1524-4725.2009.01356.x

Source DB:  PubMed          Journal:  Dermatol Surg        ISSN: 1076-0512            Impact factor:   3.398


  12 in total

Review 1.  Hemangiomas revisited: the useful, the unusual and the new. Part 2: endangering hemangiomas and treatment.

Authors:  Ricardo Restrepo; Rajaneeshankar Palani; Luisa F Cervantes; Ana-Margarita Duarte; Ibrahim Amjad; Nolan R Altman
Journal:  Pediatr Radiol       Date:  2011-05-24

2.  Superficial hemangioma is better treated by topical 5-aminolevulinic followed by 595-nm pulsed dye laser therapy rather than 595-nm laser therapy alone.

Authors:  Ming Zeng; Songke Shen; Wei Chen; Chunjun Yang; ShengXiu Liu
Journal:  Lasers Med Sci       Date:  2017-08-16       Impact factor: 3.161

3.  One Possible Mechanism of Pulsed Dye Laser Treatment on Infantile Hemangioma: Induction of Endothelial Apoptosis and Serum vascular endothelial growth factor (VEGF) Level Changes.

Authors:  Yongqian Cao; Fagang Wang; Qingwei Jia; Rongjian Xu; Wei Dang; Qing Chen; Li Lin; Yibing Wang
Journal:  J Lasers Med Sci       Date:  2014

4.  Timing and Efficacy of 595-nm Pulsed-Dye Laser Combined with 0.5% Timolol Maleate Solution in the Treatment of Superficial Infantile Hemangiomas.

Authors:  Weikang Shi; Huiyi He; Jicong Jiang; Yu Gao; Hehe Quan
Journal:  Clin Cosmet Investig Dermatol       Date:  2021-11-02

Review 5.  Visible light. Part I: Properties and cutaneous effects of visible light.

Authors:  Evan Austin; Amaris N Geisler; Julie Nguyen; Indermeet Kohli; Iltefat Hamzavi; Henry W Lim; Jared Jagdeo
Journal:  J Am Acad Dermatol       Date:  2021-02-25       Impact factor: 11.527

6.  An exploration of optimal time and safety of 595-nm pulsed dye laser for the treatment of early superficial infantile hemangioma.

Authors:  Hui-Yi He; Wei-Kang Shi; Ji-Cong Jiang; Yu Gao; Xi-Mao Xue
Journal:  Dermatol Ther       Date:  2022-03-09       Impact factor: 3.858

7.  Management of infantile hemangiomas: current trends.

Authors:  Gomathy Sethuraman; Vamsi K Yenamandra; Vishal Gupta
Journal:  J Cutan Aesthet Surg       Date:  2014-04

8.  Pulsed dye laser and topical timolol gel versus pulse dye laser in treatment of infantile hemangioma: A double-blind randomized controlled trial.

Authors:  Ali Asilian; Fatemeh Mokhtari; Atefeh Sadat Kamali; Bahareh Abtahi-Naeini; Mohammad Ali Nilforoushzadeh; Shayan Mostafaie
Journal:  Adv Biomed Res       Date:  2015-11-30

9.  Noteworthy effects of a long-pulse Alexandrite laser for treatment of high-risk infantile hemangioma: A case report and literature review.

Authors:  Wen-Ting Su; Ji-Xin Xue; You-Hui Ke
Journal:  World J Clin Cases       Date:  2019-07-26       Impact factor: 1.337

10.  Oral propranolol combined with topical timolol for compound infantile hemangiomas: a retrospective study.

Authors:  Jing Ge; Jiawei Zheng; Ling Zhang; Weien Yuan; Haiguang Zhao
Journal:  Sci Rep       Date:  2016-01-28       Impact factor: 4.379

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